Human placental development involves co-ordinated angiogenesis and trophoblast
outgrowth that are compromised in intrauterine growth restriction. Adaptive angiogenesis in …

Insufficient oxygen leads to the cessation of growth in favor of cellular survival. Our unique
model of high-altitude human pregnancy indicates that hypoxia-induced reductions in fetal …

OBJECTIVES: Our purpose was to investigate a possible role for apoptosis in the
pathophysiologic mechanisms of intrauterine growth restriction. STUDY DESIGN: Placental …

In rodents and humans there is a sexually dimorphic pattern of GH secretion that influences
the serum concentration of IGF-I. Pattern differences can be identified in children, but it is not …

Fetal overgrowth and higher adiposity are hallmarks of pregnancy with maternal obesity and
poor glucose tolerance, two conditions associated with decreased maternal insulin …

The relationship between GH, insulin-like growth factor I (IGF-I), IGF-binding protein-1
(IGFBP-1), and insulin may be critical to the understanding of variation in early growth …

Several epidemiologic studies have demonstrated that high birthweight is associated with
an increased risk of infant leukemia; however, the reason for this relationship is unclear …

The cause of hyperglycemia in extremely-low-birth-weight (ELBW) infants is not well
understood. We studied infants weighing< 1,000 g to investigate the relationship of …

Objective: The objective was to compare dual-energy x-ray absorptiometry–measured body
composition between large (LGA) and appropriate (AGA) birth weight for gestational age …

Intrauterine growth retardation (IUGR) is defined as growth retarded to be below the tenth
centile. The insulin‐like growth factors and their receptors are implicated in pre‐and …