Progression in translational research on spinal cord injury based on microenvironment imbalance

B Fan, Z Wei, S Feng - Bone research, 2022 - nature.com
Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level
and imposes a considerable burden on patients, families, and society. Repair of the injured …

Collagen-based biomaterials for tissue engineering

Y Wang, Z Wang, Y Dong - ACS Biomaterials Science & …, 2023 - ACS Publications
Collagen is commonly used as a regenerative biomaterial due to its excellent
biocompatibility and wide distribution in tissues. Different kinds of hybridization or cross-links …

A DAMP-scavenging, IL-10-releasing hydrogel promotes neural regeneration and motor function recovery after spinal cord injury

H Shen, B Xu, C Yang, W Xue, Z You, X Wu, D Ma… - Biomaterials, 2022 - Elsevier
Spinal cord injury (SCI) creates an inflammatory microenvironment characterized by
damage-associated molecular patterns (DAMPs) and immune cell activation that exacerbate …

[HTML][HTML] An injectable, self-healing, electroconductive extracellular matrix-based hydrogel for enhancing tissue repair after traumatic spinal cord injury

Y Luo, L Fan, C Liu, H Wen, S Wang, P Guan, D Chen… - Bioactive materials, 2022 - Elsevier
Injectable biomaterial-based treatment is a promising strategy to enhance tissue repair after
traumatic spinal cord injury (SCI) by bridging cavity spaces. However, there are limited …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

Bioactive injectable hydrogels for on demand molecule/cell delivery and for tissue regeneration in the central nervous system

MA Grimaudo, GS Krishnakumar, E Giusto, F Furlani… - Acta biomaterialia, 2022 - Elsevier
Currently there are no potential curative therapies that can improve the central nervous
system (CNS) regeneration after traumatic injuries or diseases. Indeed, the regeneration of …

[HTML][HTML] Collagen for neural tissue engineering: Materials, strategies, and challenges

WH Huang, SL Ding, XY Zhao, K Li, HT Guo… - Materials Today Bio, 2023 - Elsevier
Neural tissue engineering (NTE) has made remarkable strides in recent years and holds
great promise for treating several devastating neurological disorders. Selecting optimal …

Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

Selenium-doped carbon quantum dots efficiently ameliorate secondary spinal cord injury via scavenging reactive oxygen species

W Luo, Y Wang, F Lin, Y Liu, R Gu, W Liu… - International journal of …, 2020 - Taylor & Francis
Background: The excess production of reactive oxygen species (ROS) after traumatic spinal
cord injury (TSCI) has been identified as a leading cause of secondary injury, which can …

Harnessing the power of biological macromolecules in hydrogels for controlled drug release in the central nervous system: A review

S Ghosh, S Ghosh, H Sharma, R Bhaskar… - International Journal of …, 2024 - Elsevier
Hydrogels have immense potential in revolutionizing central nervous system (CNS) drug
delivery, improving outcomes for neurological disorders. They serve as promising tools for …