ROS/mtROS promotes TNTs formation via the PI3K/AKT/mTOR pathway to protect against mitochondrial damages in glial cells induced by engineered nanomaterials
X Lin, W Wang, X Chang, C Chen, Z Guo, G Yu… - Particle and Fibre …, 2024 - Springer
Background As the demand and application of engineered nanomaterials have increased,
their potential toxicity to the central nervous system has drawn increasing attention …
their potential toxicity to the central nervous system has drawn increasing attention …
Invisible Bridges: Unveiling the Role and Prospects of Tunneling Nanotubes in Cancer Therapy
M Chen, D Zhao - Molecular Pharmaceutics, 2024 - ACS Publications
Tunneling nanotubes (TNTs) are essential intercellular communication channels that
significantly impact cancer pathophysiology, affecting tumor progression and resistance …
significantly impact cancer pathophysiology, affecting tumor progression and resistance …
[HTML][HTML] The role of mitochondria transfer in cancer biological behavior, the immune system and therapeutic resistance
X Lyu, Y Yu, Y Jiang, Z Li, Q Qiao - Journal of Pharmaceutical Analysis, 2024 - Elsevier
Mitochondria play a crucial role as organelles, managing several physiological processes
such as redox balance, cell metabolism, and energy synthesis. Initially, the assumption was …
such as redox balance, cell metabolism, and energy synthesis. Initially, the assumption was …
Tunneling nanotubes between bone marrow stromal cells support transmitophagy and resistance to apoptosis in myeloma
Hypoxia and glucose deprivation drive metabolic reprogramming in MM cells [2], reducing
mitochondrial activity [3] while enhancing their reliance on glycolysis via the Warburg effect …
mitochondrial activity [3] while enhancing their reliance on glycolysis via the Warburg effect …
Deciphering the CNS-glioma dialogue: Advanced insights into CNS-glioma communication pathways and their therapeutic potential
L Zhang, Y Wang, X Cai, X Mao… - Journal of Central …, 2024 - journals.sagepub.com
The field of cancer neuroscience has rapidly evolved, shedding light on the complex
interplay between the nervous system and cancer, with a particular focus on the relationship …
interplay between the nervous system and cancer, with a particular focus on the relationship …
Glioma Stem Cells—Features for New Therapy Design
N Pećina-Šlaus, R Hrašćan - Cancers, 2024 - mdpi.com
Simple Summary Gliomas are deleterious central nervous system tumors that harbor cellular
heterogeneity and infiltrative capabilities. They are biologically aggressive and highly …
heterogeneity and infiltrative capabilities. They are biologically aggressive and highly …
Miro-mediated mitochondrial transport: A new dimension for disease-related abnormal cell metabolism?
Y Li, Z Yang, S Zhang, J Li - Biochemical and Biophysical Research …, 2024 - Elsevier
Mitochondria are versatile and highly dynamic organelles found in eukaryotic cells that play
important roles in a variety of cellular processes. The importance of mitochondrial transport …
important roles in a variety of cellular processes. The importance of mitochondrial transport …