Under acidic reaction conditions (TFA), deprotection of BocNR (OSO2R) reagents triggers
intermolecular aminative cyclizations of alkenes equipped with pendant nucleophiles. The …

We recently established that drugs used for the treatment and the prophylaxis of breast
cancers, such as tamoxifen, were potent inhibitors of cholesterol-5, 6-epoxide hydrolase …

Metalated nitriles are nucleophilic chameleons whose precise identity is determined by the
nature of the metal, the solvent, the temperature, and the structure of the nitrile. The review …

Tandem driven dynamic combinatorial resolution via Henry–iminolactone rearrangement -
Chemical Communications (RSC Publishing) DOI:10.1039/B716521H Royal Society of …

A valuable umpolung strategy that highlights the ambiphilic nature of the bis (phenylsulfonyl)
methyl synthon and demonstrates its utility as a synthetic linchpin is reported. Although the …

Adding organolithiums, Grignard reagents, or zincates to sulfinylnitriles triggers a facile
sulfinyl–metal exchange to afford N‐or C‐metalated nitriles. Sulfinyl–magnesium exchange …

The first total synthesis of amphiasterin B4, a secondary metabolite previously isolated from
Plakortis quasiamphiaster has been achieved. The core structure has been reached …

The diastereoselective synthesis of pentacarbonyl-3-oxa-2-bicyclo [3.1. 0] hexylidene-and
pentacarbonyl (cyclopropylmethoxymethylene) tungsten compounds 4 and 9 by the reaction …

The rational choice of a hydroxy protecting group, as shown by molecular modeling studies
and experimentally confirmed, is a key issue for the success of the first total synthesis of an …

The novel carbapenem precursor 1e has been synthesized from l‐threonine, cyclopropyl
methyl ketone and benzhydrylamine (for the introduction of the azetidinone N‐protecting …