UV-induced DNA damage plays a key role in the initiation phase of skin cancer. When left
unrepaired or when damaged cells are not eliminated by apoptosis, DNA lesions express …

The fields of theoretical and computational chemistry have come a long way since their
inception in the mid-20th century. Fifty years ago, only rudimentary approximations for very …

Emphasis has been placed in this article dedicated to DNA damage on recent aspects of the
formation and measurement of oxidatively generated damage in cellular DNA in order to …

Over the last few decades, conical intersections (CoIns) have grown from theoretical
curiosities into common mechanistic features of photochemical reactions, whose function is …

DNA owes its remarkable photostability to its building blocks—the nucleosides—that
efficiently dissipate the energy acquired upon ultraviolet light absorption. The mechanism …

The survey focuses on recent aspects of photochemical reactions to cellular DNA that are
implicated through the predominant formation of mostly bipyrimidine photoproducts in …

Crossings of electronic potential energy surfaces in nuclear configuration space, known as
conical intersections, determine the rates and outcomes of a large class of photochemical …

Azetines, four-membered unsaturated nitrogen-containing heterocycles, hold great potential
for drug design and development but remain underexplored due to challenges associated …

This review chapter presents a critical survey of the main available information on the UVB
and UVA bipyrimidine photoproducts which constitute the predominant recipient classes of …

Ultraviolet (UV) radiation is a leading external hazard to the integrity of DNA. Exposure to UV
radiation triggers a cascade of chemical reactions, and many molecular products …