The heterogeneity of tissue macrophages, in health and in disease, has become
increasingly transparent over the last decade. But with the plethora of data comes a natural …

Myeloid cells represent a dominant cellular compartment of tumor lesions and play key roles
in tumor inception, progression, metastasis, and response to treatment. Mononuclear …

Pancreatic ductal adenocarcinoma (PDA) orchestrates a suppressive tumor
microenvironment that fosters immunotherapy resistance. Tumor-associated macrophages …

Chronic pancreatitis (CP) is characterized by chronic progressive pancreatic inflammation,
which leads to the permanent damage of exocrine and endocrine cells. CP causes …

Myeloid cells are increasingly being recognized as central players orchestrating or
suppressing antitumor immune responses. With the advent of high-resolution analytical …

The two faces of pancreas tissue-resident macrophages | Nature Reviews Immunology Skip to
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Pancreatic ductal adenocarcinoma (PDA) is a lethal malignancy resistant to immunotherapy.
The pancreatic tumor microenvironment is shaped and maintained by myeloid cells that …