Chromatin remodelling drives immune cell–fibroblast communication in heart failure

M Alexanian, A Padmanabhan, T Nishino, JG Travers… - Nature, 2024 - nature.com
Chronic inflammation and tissue fibrosis are common responses that worsen organ function,
yet the molecular mechanisms governing their cross-talk are poorly understood. In diseased …

Engineered Cardiac Tissues as a Platform for CRISPR‐Based Mitogen Discovery

S DeLuca, N Strash, Y Chen, M Patsy… - Advanced …, 2025 - Wiley Online Library
Improved understanding of cardiomyocyte (CM) cell cycle regulation may allow researchers
to stimulate pro‐regenerative effects in injured hearts or promote maturation of human stem …

The Applications of CRISPR Screening in Aging Research.

XU Jia-Xin, J Yao-Bin, QU Jing… - Chinese Journal of …, 2024 - search.ebscohost.com
Abstract The advancement of Clustered Regularly Interspaced Short Palindromic Repeats
(CRISPR) gene editingtechnologyhasrevolutionizedthecom…, propellingmolecularand …