Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …

▪ Abstract Many metazoan cells inhabit mechanically stressful environments and,
consequently, their plasma membranes are frequently disrupted. Survival requires that the …

Lysosomes are considered to be a terminal degradative compartment of the endocytic
pathway, into which transport is mostly unidirectional. However, specialized secretory …

Trypanosoma cruzi, the causative agent of Chagas′ disease, which affects a large number
of individuals in Central and South America, is transmitted to vertebrate hosts by blood …

Trypanosoma cruzi is the etiologic agent of Chagas disease, a neglected tropical disease
that affects millions of people mainly in Latin America. To establish a life-long infection, T …

Chagas disease is a debilitating human illness caused by infection with the protozoan
Trypanosoma cruzi. A capacity to invade and replicate within many different cell types is a …

Establishment of infection by Trypanosoma cruzi, the agent of Chagas' disease, depends on
a series of events involving interactions of diverse parasite molecules with host components …

Infection with the protozoan parasite Trypanosoma cruzi, the agent of Chagas disease, is
characterised by a variable clinical course–from symptomless cases to severe chronic …

The innate immune system is the first mechanism of vertebrate defense against pathogen
infection. In this study, we present evidence for a novel immune evasion mechanism of …

The protozoan parasite, Trypanosoma cruzi, causes the Chagas' disease in humans through
infection of mammalian cells in both vertebrate and invertebrate hosts. Transmission of the …