Mechanistic insights into the crystallization of coamorphous drug systems

W Heng, Y Song, M Luo, E Hu, Y Wei, Y Gao… - Journal of Controlled …, 2023 - Elsevier
In our previous study, the coamorphous formulation of lurasidone hydrochloride (LH) with
saccharin (SAC) showed significantly enhanced dissolution and physical stability compared …

Gelation switch of polyamorphic indomethacin depending on the thermal procedure

P Shen, C Zhang, E Hu, Z Pang, Y Gao, S Qian… - European Journal of …, 2022 - Elsevier
Amorphous indomethacin (IMC) prepared under different thermal procedures via melt
quenching method showed significantly different dissolution behaviors. This study aims to …

Surface tension of binary mixtures of (ionic liquid+ tributyl phosphate)

Z Li, Y Sun, D Zhao, Y Zhuang, R Wang, F Yang… - The Journal of Chemical …, 2019 - Elsevier
In this work, surface tension was determined for binary mixtures of imidazolium based ionic
liquids (ILs) and tributyl phosphate (TBP) over the whole composition range at temperatures …

[HTML][HTML] Structural analysis of water in ionic liquid domains–A low pressure study

K Dziubinska-Kühn, J Croese, M Pupier… - Journal of Molecular …, 2021 - Elsevier
Imidazolium-based ionic liquids (ILs) are frequently used solvents, due to their peculiar
structure resulting in low melting points. Recent studies revealed the direct impact of the …

The potential of supramolecular synthon to develop coamorphous systems with tailored physical stability: Mechanistic insights integrating kinetics and …

Y Song, Y Chen, W Heng, E Hu, Y Shi, Y Gao… - International Journal of …, 2024 - Elsevier
Coamorphous drug delivery systems have received increasing interest owing to their
potential to improve the solubility, dissolution and bioavailability of poorly water-soluble …

Ordering of ionic liquids at a charged sapphire interface: Evolution with cationic chain length

D Pontoni, M DiMichiel, BM Murphy… - Journal of Colloid and …, 2024 - Elsevier
Abstract Hypothesis Room Temperature Ionic Liquids (RTILs) bulk's molecular layering
dominates their structure also at the RTIL/sapphire interface, increasing the layer spacing …

Interfacial forces in free-standing layers of melted polyethylene, from critical to nanoscopic thicknesses

FI Ramírez-Zavaleta, VM Torres-Dominguez… - Polymers, 2022 - mdpi.com
Molecular dynamics simulations of ultrathin free-standing layers made of melted (373.15–
673.15 K) polyethylene chains, which exhibit a lower melting temperature (compared to the …

Critical Thickness of Free-Standing Nanothin Films Made of Melted Polyethylene Chains via Molecular Dynamics

JA González-Mijangos, E Lima, R Guerra-González… - Polymers, 2021 - mdpi.com
The mechanical stability of nanothin free-standing films made of melted polyethylene chains
was predicted via molecular dynamics simulations in the range of 373.15–673.15 K. The …

Influence of film thickness on the stability of free-standing Lennard-Jones fluid films

JL Rivera, JF Douglas - The Journal of Chemical Physics, 2019 - pubs.aip.org
Molecular dynamics simulations of thin free-standing Lennard-Jones fluid films were carried
out with a view of establishing the thickness range over which such films are …

Probing the electronic structure of ether functionalised ionic liquids using X-ray photoelectron spectroscopy

EJ Dick, AEA Fouda, NA Besley… - Physical Chemistry …, 2020 - pubs.rsc.org
The charge distribution associated with individual components in functionalised ionic liquids
(ILs) can be tuned by careful manipulation of the substituent groups incorporated into the …