American Society of Clinical Oncology 2007 update of recommendations for the use of tumor markers in breast cancer

L Harris, H Fritsche, R Mennel, L Norton… - Journal of clinical …, 2007 - ascopubs.org
Purpose To update the recommendations for the use of tumor marker tests in the prevention,
screening, treatment, and surveillance of breast cancer. Methods For the 2007 update, an …

Dissecting the metastatic cascade

K Pantel, RH Brakenhoff - Nature reviews cancer, 2004 - nature.com
Despite recent progress in gene-expression profiling studies, the biology underlying the
various patterns of metastasis that are observed in different tumour types remains unclear …

A pooled analysis of bone marrow micrometastasis in breast cancer

S Braun, FD Vogl, B Naume, W Janni… - New England journal …, 2005 - Mass Medical Soc
Background We assessed the prognostic significance of the presence of micrometastasis in
the bone marrow at the time of diagnosis of breast cancer by means of a pooled analysis …

Clinical, cellular, and molecular aspects of cancer invasion

M Mareel, A Leroy - Physiological reviews, 2003 - journals.physiology.org
Invasion causes cancer malignancy. We review recent data about cellular and molecular
mechanisms of invasion, focusing on cross-talk between the invaders and the host. Cancer …

Skin-sparing mastectomy with conservation of the nipple–areola complex and autologous reconstruction is an oncologically safe procedure

B Gerber, A Krause, T Reimer, H Müller… - Annals of …, 2003 - journals.lww.com
Skin-Sparing Mastectomy with Conservation of the Nipple–Areo... : Annals of Surgery Skin-Sparing
Mastectomy with Conservation of the Nipple–Areola Complex and Autologous Reconstruction …

Significance, detection and markers of disseminated breast cancer cells

M Lacroix - Endocrine-related cancer, 2006 - erc.bioscientifica.com
The development of distant metastases is the major cause of death from breast cancer. In
order to predict and prevent tumour spreading, many attempts are being made to detect …

Biological relevance of disseminated tumor cells in cancer patients

S Riethdorf, H Wikman, K Pantel - International journal of …, 2008 - Wiley Online Library
The prognosis of cancer patients is largely determined by the occurrence of distant
metastases. In patients with primary tumors, this relapse is mainly due to clinically occult …

[HTML][HTML] Genomic analysis of single cytokeratin-positive cells from bone marrow reveals early mutational events in breast cancer

JA Schardt, M Meyer, CH Hartmann, F Schubert… - Cancer cell, 2005 - cell.com
Chromosomal instability in human breast cancer is known to take place before mammary
neoplasias display morphological signs of invasion. We describe here the unexpected …

A concept for the standardized detection of disseminated tumor cells in bone marrow from patients with primary breast cancer and its clinical implementation

T Fehm, S Braun, V Muller, W Janni… - … Journal of the …, 2006 - Wiley Online Library
Numerous single‐institutional studies and a large pooled analysis have demonstrated that
the presence of disseminated tumor cells (DTCs) in the bone marrow (BM) from patients with …

Clinical significance of immunocytochemical detection of tumor cells using digital microscopy in peripheral blood and bone marrow of breast cancer patients

JY Pierga, C Bonneton, A Vincent-Salomon… - Clinical Cancer …, 2004 - AACR
Purpose: The presence of tumor cells in bone marrow has been reported to represent an
important prognostic indicator in breast cancer, but the clinical significance of circulating …