Acetaminophen induced hepatotoxicity: An overview of the promising protective effects of natural products and herbal formulations

S Chilvery, A Yelne, A Khurana, MA Saifi, S Bansod… - Phytomedicine, 2023 - Elsevier
Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …

[HTML][HTML] Novel therapies for the treatment of drug-induced liver injury: a systematic review

MS Benić, L Nežić, V Vujić-Aleksić… - Frontiers in …, 2022 - frontiersin.org
Many drugs with different mechanisms of action and indications available on the market
today are capable of inducing hepatotoxicity. Drug-induced liver injury (DILI) has been a …

Dietary chitosan nanoparticles enhance the growth, production performance, and immunity in Oreochromis niloticus

FS Abd El-Naby, MAE Naiel, AA Al-Sagheer, SS Negm - Aquaculture, 2019 - Elsevier
The use of safe supplements for the enhancement of fish production and health are vital for
future advancement in aquaculture. A trial was carried out to explore the influence of …

Evaluation of dietary chitosan effects on growth performance, immunity, body composition and histopathology of Nile tilapia (Oreochromis niloticus) as well as the …

SE Fadl, GA El‐Gammal, WS Abdo… - Aquaculture …, 2020 - Wiley Online Library
The present investigation aimed to evaluate the effect of dietary chitosan supplementation
on growth performance, body composition, immune response and histopathology of Nile …

Prevention of hepatic stellate cell activation using JQ1-and atorvastatin-loaded chitosan nanoparticles as a promising approach in therapy of liver fibrosis

R Hassan, SN Tammam, S El Safy… - European Journal of …, 2019 - Elsevier
Preventing hepatic stellate cell (HSC) activation represents a promising approach to resolve
liver fibrosis. Several drugs have been reported to delay/prevent HSCs activation, however …

[HTML][HTML] Morin encapsulated chitosan nanoparticles (MCNPs) ameliorate arsenic induced liver damage through improvement of the antioxidant system and prevention …

S Mondal, S Das, PK Mahapatra, KD Saha - Nanoscale Advances, 2022 - pubs.rsc.org
Chronic exposure to arsenic over a period of time induces toxicity, primarily in the liver but
gradually in all systems of the body. Morin hydrate (MH; 2′, 3, 4′, 5, 7 …

Pharmacological and biological effects of chitosan

B Anna, D Solaiman, S Alexey… - Research Journal of …, 2020 - indianjournals.com
This article is devoted to the analysis and synthesis of published data of the structure,
physicochemical properties, sources of production and biological effects of chitosan, which …

Natural remedies for non‐steroidal anti‐inflammatory drug‐induced toxicity

JP Simon, S Evan Prince - Journal of Applied Toxicology, 2017 - Wiley Online Library
The liver is an important organ of the body, which has a vital role in metabolic functions. The
non‐steroidal anti‐inflammatory drug (NSAID), diclofenac causes hepato‐renal toxicity and …

[HTML][HTML] Therapeutic effect of chitosan on CCl4‑induced hepatic fibrosis in rats

ZF Wang, MY Wang, DH Yu… - Molecular …, 2018 - spandidos-publications.com
Chitosan is a linear polysaccharide that is made by treating the chitin shells of shrimp and
crustaceans with an alkaline substance, for example sodium hydroxide. Due to its unique …

Nicotinamide and ascorbic acid nanoparticles against the hepatic insult induced in rats by high fat high fructose diet: A comparative study

H Abd-Allah, M Nasr, OAH Ahmed-Farid, BMM Ibrahim… - Life Sciences, 2020 - Elsevier
Aims Non-alcoholic fatty liver disease (NAFLD) caused by consumption of high levels of fat
and sugars (HFHS) in diet is considered one of the most dangerous medical complications …