The 40-year history of modeling active dendrites in cerebellar Purkinje cells: emergence of the first single cell “community model”
JM Bower - Frontiers in computational neuroscience, 2015 - frontiersin.org
The subject of the effects of the active properties of the Purkinje cell dendrite on neuronal
function has been an active subject of study for more than 40 years. Somewhat unusually …
function has been an active subject of study for more than 40 years. Somewhat unusually …
Purkinje cell models: past, present and future
EM Fernández Santoro, A Karim, P Warnaar… - Frontiers in …, 2024 - frontiersin.org
The investigation of the dynamics of Purkinje cell (PC) activity is crucial to unravel the role of
the cerebellum in motor control, learning and cognitive processes. Within the cerebellar …
the cerebellum in motor control, learning and cognitive processes. Within the cerebellar …
Analysis of noise effects in a map-based neuron model with Canard-type quasiperiodic oscillations
I Bashkirtseva, V Nasyrova, L Ryashko - Communications in Nonlinear …, 2018 - Elsevier
A problem of the mathematical modeling and analysis of the complex mixed-mode
stochastic oscillations in neural activity is studied. For the description of noise-induced …
stochastic oscillations in neural activity is studied. For the description of noise-induced …
An elementary model of torus canards
We study the recently observed phenomena of torus canards. These are a higher-
dimensional generalization of the classical canard orbits familiar from planar systems and …
dimensional generalization of the classical canard orbits familiar from planar systems and …
Conditional bistability, a generic cellular mnemonic mechanism for robust and flexible working memory computations
G Rodriguez, M Sarazin, A Clemente… - Journal of …, 2018 - Soc Neuroscience
Persistent neural activity, the substrate of working memory, is thought to emerge from
synaptic reverberation within recurrent networks. However, reverberation models do not …
synaptic reverberation within recurrent networks. However, reverberation models do not …
Long‐lasting small‐amplitude TRP‐mediated dendritic depolarizations in CA1 pyramidal neurons are intrinsically stable and originate from distal tuft regions
ME Petersson, E Fransén - European Journal of Neuroscience, 2012 - Wiley Online Library
In several regions of the nervous system, neurons display bi‐or multistable intrinsic
properties. Such stable states may be subthreshold and long‐lasting, and can appear as a …
properties. Such stable states may be subthreshold and long‐lasting, and can appear as a …
The emergence of community models in computational neuroscience: The 40-Year history of the cerebellar Purkinje cell
JM Bower - 20 years of computational neuroscience, 2013 - Springer
The previous chapter in this volume considers the 20-year development of technology
supporting the reuse and reproducibility of computational models. This chapter considers …
supporting the reuse and reproducibility of computational models. This chapter considers …
The role of relative membrane capacitance and time delay in cerebellar Purkinje cells
J Wang, S Liu, B Lu, Y Zeng - … Engineering/Biomedizinische Technik, 2017 - degruyter.com
The membrane capacitance of a neuron can influence the synaptic efficacy and the speed of
electrical signal propagation. Exploring the role of membrane capacitance will help facilitate …
electrical signal propagation. Exploring the role of membrane capacitance will help facilitate …
Modelling cerebellar Purkinje cells with simple neuron models of the threshold type
EP Lynch, CJ Houghton - BMC Neuroscience, 2013 - Springer
In the cerebellum, cells receive external input from only two sources, climbing fibres and
mossy fibres [1]. Mossy fibres excite granule cells whose axons, called parallel fibres …
mossy fibres [1]. Mossy fibres excite granule cells whose axons, called parallel fibres …