[HTML][HTML] Fluid flow to mimic organ function in 3D in vitro models

Y Juste-Lanas, S Hervas-Raluy, JM García-Aznar… - APL …, 2023 - pubs.aip.org
Many different strategies can be found in the literature to model organ physiology, tissue
functionality, and disease in vitro; however, most of these models lack the physiological fluid …

Microfluidic techniques for mechanical measurements of biological samples

PF Salipante - Biophysics Reviews, 2023 - pubs.aip.org
The use of microfluidics to make mechanical property measurements is increasingly
common. Fabrication of microfluidic devices has enabled various types of flow control and …

A bone‐on‐a‐chip collagen hydrogel‐based model using pre‐differentiated adipose‐derived stem cells for personalized bone tissue engineering

P Alamán‐Díez, E García‐Gareta… - … Research Part A, 2023 - Wiley Online Library
Mesenchymal stem cells have contributed to the continuous progress of tissue engineering
and regenerative medicine. Adipose‐derived stem cells (ADSC) possess many advantages …

Human Cell‐Derived Matrix Composite Hydrogels with Diverse Composition for Use in Vasculature‐on‐chip Models

EL Doherty, G Krohn, EC Warren… - Advanced …, 2024 - Wiley Online Library
Microphysiological and organ‐on‐chip platforms seek to address critical gaps in human
disease models and drug development that underlie poor rates of clinical success for novel …

Integrated role of human thymic stromal cells in hematopoietic stem cell extravasation

SA Watson, Y Javanmardi, L Zanieri… - Bioengineering & …, 2023 - Wiley Online Library
The human thymus is the site of T‐cell maturation and induction of central tolerance.
Hematopoietic stem cell (HSC)‐derived progenitors are recruited to the thymus from the fetal …

A human initial lymphatic chip reveals distinct mechanisms of primary lymphatic valve dysfunction in acute and chronic inflammation

S Kraus, E Lee - Lab on a Chip, 2023 - pubs.rsc.org
Interstitial fluid uptake and retention by lymphatic vessels (LVs) play a role in maintaining
interstitial fluid homeostasis. While it is well-established that intraluminal lymphatic valves in …

A microfluidic-based analysis of 3D macrophage migration after stimulation by Mycobacterium, Salmonella and Escherichia

S Pérez-Rodríguez, C Borau, JM García-Aznar… - BMC microbiology, 2022 - Springer
Macrophages play an essential role in the process of recognition and containment of
microbial infections. These immune cells are recruited to infectious sites to reach and …

In vitro models of blood and lymphatic vessels—connecting tissues and immunity

A Bogseth, A Ramirez, E Vaughan… - Advanced biology, 2023 - Wiley Online Library
Blood and lymphatic vessels are regulators of physiological processes, including
oxygenation and fluid transport. Both vessels are ubiquitous throughout the body and are …

A multicellular vessel-on-a-chip model reveals context-dependent roles for platelets in inflammation and inflammatory hemostasis

RB Riddle, K Jennbacken, KM Hansson… - Blood Vessels …, 2024 - ashpublications.org
The immune system identifies and destroys invading pathogens. However, chronic
inflammation and excessive tissue damage can occur if inflammation is not resolved or if the …

Intelligent Microfluidics Research on Relative Permeability Measurement and Prediction of Two‐Phase Flow in Micropores

H Song, C Liu, J Lao, J Wang, S Du, M Yu - Geofluids, 2021 - Wiley Online Library
Relative permeability is a key index in resource exploitation, energy development,
environmental monitoring, and other fields. However, the current determination methods of …