The epidemiology of foot-and-mouth disease (FMD) in Africa is unique in the sense that six
of the seven serotypes of FMD viruses (Southern African Territories [SAT] 1, SAT2, SAT3, A …

This study assessed research knowledge gaps in the field of FMDV (foot‐and‐mouth
disease virus) vaccines. The study took the form of a literature review (2011–15) combined …

Although several different flaviviruses may cause encephalitis, Japanese encephalitis virus
is the most significant, being responsible for thousands of deaths each year in Asia. The …

Metastatic pancreatic ductal adenocarcinomas (PDAC) are incurable due to the rapid
development of resistance to all current therapeutics. Oncolytic adenoviral mutants have …

Short linear motifs (SLiM) are short peptides that facilitate protein function and protein-
protein interactions. Viruses utilize these motifs to enter into the host, interact with cellular …

Foot-and-mouth disease (FMD), an acute, violent, infectious disease of cloven-hoofed
animals, remains widespread in most parts of the world. It can lead to a major plague of …

Foot-and-mouth disease is endemic in livestock in large parts of Africa and Asia, where it is
an important driver of food insecurity and a major obstacle to agricultural development and …

Virus entry is an attractive target for therapeutic intervention. Here, using a combination of
electron microscopy, immunofluorescence assay, siRNA interference, specific …

Background Suspension culture of BHK cells allows large-scale virus propagation and cost-
efficient vaccine production, while the shift to animal-component-free cell culture media …

The presence of sequence divergence through adaptive mutations in the major capsid
protein VP1, and also in VP0 (VP4 and VP2) and VP3, of foot-and-mouth disease virus …