[HTML][HTML] Substituting azobenzene for proline in melittin to create photomelittin: A light-controlled membrane active peptide

CR Ventura, GR Wiedman - Biochimica et Biophysica Acta (BBA) …, 2021 - Elsevier
In this article we present the synthesis and characterization of a new form of the membrane
active peptide melittin: photomelittin. This peptide was created by substituting the proline …

Molecularly Imprinted Chalcone-Branched Polyimide-Based Chemosensors with Stripe Nanopatterns for the Detection of Melittin

JC Yang, J Lee, SJ Lim, G Kwak, J Park - ACS sensors, 2023 - ACS Publications
In this study, a chalcone-branched polyimide (CB-PI) was synthesized by the Steglich
esterification reaction for selective recognition of the toxic peptide melittin (MEL). MEL was …

High-performance liquid chromatography combined with intrinsic fluorescence detection to analyse melittin in individual honeybee (Apis mellifera) venom sac

J Dong, B Ying, S Huang, S Ma, P Long, X Tu… - … of Chromatography B, 2015 - Elsevier
Melittin is the major toxin peptide in bee venom, which has diverse biological effects. In the
present study, melittin was separated by reverse-phase high-performance liquid …

Innovative separation of melittin from bee venom using micro-free-flow electrophoresis: An experimental and theoretical study

A Kordzadeh, AR Sa, S Mashayekhan - Analytica Chimica Acta, 2025 - Elsevier
Background Bee venom consists of more than 50% melittin (MLT), which has anti-cancer,
anti-inflammatory, and antimicrobial properties. Bee venom also contains toxic components …

Quantitative measurement of melittin in Asian honeybee venom using a new method including UPLC-QqTOF-MS

S Huang, J Wang, Z Guo, Y Wang, C Liu - Toxins, 2020 - mdpi.com
Asian honeybee venom is widely used in traditional oriental medicine. Melittin is the main
component of Asian honeybee venom. In the present study, an ultra-performance liquid …

In vivo neutralization of bee venom lethality by IgY antibodies

CL Leiva, P Geoghegan, M Lammer, A Cangelosi… - Molecular …, 2021 - Elsevier
Bee venom is a complex mixture of molecules, among which melittin and phospholipase A 2
(PLA 2) are the toxic components involved in envenoming accidents with multiple honeybee …

Bee venom and melittin: Potent key enzyme inhibitors with promising therapeutic potential

B Alparslan, M Şentürk, C Erkan - Toxicon, 2024 - Elsevier
Bee venom (BV) is a versatile product with extensive applications, boasting antibacterial and
anticancer properties. Within this study, we focused on isolating melittin (Mel) from Apis …

A validated extraction technique followed by high‐performance liquid chromatography‐ultraviolet analysis for the assay of melittin as an indicator component of honey …

N Akhtari, K Banan, F Fatahian… - Separation …, 2024 - Wiley Online Library
Honey bee venom (HBV) is a valuable bee product famous for its therapeutic efficacy. HBV
has a complex matrix containing several compounds, of which melittin is identified as the …

[HTML][HTML] Low-dose melittin is safe for intravitreal administration and ameliorates inflammation in an experimental model of uveitis

BFM Castro, CN da Silva, LPB Cordeiro… - Current Research in …, 2022 - Elsevier
Uveitis is a group of sight-threatening ocular inflammatory disorders, whose mainstay of
therapy is associated with severe adverse events, prompting the investigation of alternative …

蜂毒肽的分离纯化及结构鉴定.

史浩川, 杨梦瑞, 王敏, 强维, 刘香艳… - Journal of Food …, 2023 - search.ebscohost.com
目的对蜂毒肽进行分离纯化, 并进行结构鉴定. 方法以意大利蜜蜂蜂毒为原料, 经溶解, 超声,
浸提, 过滤等, 并制备C18 液相色谱柱, 对一次纯化采用的流动相, 洗脱程序进行优化 …