Genes specifying long non-coding RNAs (lncRNAs) occupy a large fraction of the genomes
of complex organisms. The term 'lncRNAs' encompasses RNA polymerase I (Pol I), Pol II …

Next-generation sequencing has provided a more complete picture of the composition of the
human transcriptome indicating that much of the “blueprint” is a vastness of poorly …

Development is a complex process regulated both by genetic and epigenetic and
environmental clues. Recently, long non-coding RNAs (lncRNAs) have emerged as key …

The origin story and emergence of molecular biology is muddled. The early triumphs in
bacterial genetics and the complexity of animal and plant genomes complicate an intricate …

Understanding human embryology has historically relied on comparative approaches using
mammalian model organisms. With the advent of low-input methods to investigate genetic …

RNA–protein interaction networks govern many biological processes but are difficult to
examine comprehensively. We devised ribonucleoprotein networks analyzed by mutational …

XX female and XY male therian mammals equalize X-linked gene expression through the
mitotically-stable transcriptional inactivation of one of the two X chromosomes in female …

Long noncoding RNAs (lncRNAs) are essential regulatory elements of sex chromosomes
that act to equalize gene expression levels between males and females. XIST, RSX, and …

Simple Summary Advances in RNA sequencing (RNA-seq) have led to the identification of
long non-coding RNAs (lncRNAs). Molecular studies on these molecules have shown that …

We review how epigenetics affect sex chromosome evolution in animals and plants. In a few
species, sex is determined epigenetically through the action of Y-encoded small RNAs …