Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

Traditional hydrogels are strong candidates for biomedical applications; however, they may
suffer from drawbacks such as weak mechanics, static properties, and an inability to fully …

Hydrogels are cross-linked hydrophilic macromolecules that contain a certain amount of
water. Due to their biocompatible, highly tunable and hydrophilic nature, hydrogels have …

Purpose Age-related eye diseases are becoming more prevalent. A notable increase has
been seen in the most common causes including glaucoma, age-related macular …

Topical instillation of eye drops remains the most common and easiest route of ocular drug
administration, representing the treatment of choice for many ocular diseases. Nevertheless …

Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …

Natural cross-linkers are extensively employed due to their low toxicity and biocompatibility
benefits. Genipin acts as a precursor for producing blue colorants. The formation of these …

A wide variety of smart polymer systems such as thermosensitive polymers (TSPs) have
been developed and applied mimicking nature. TSPs are a class of macromolecules that …

Genipin is a naturally occurring nontoxic cross-linker, which has been widely used for drug
delivery due to its excellent biocompatibility, admirable biodegradability and stable cross …

There are many challenges involved in ocular drug delivery. These are a result of the many
tissue barriers and defense mechanisms that are present with the eye; such as the cornea …