Serine integrases: advancing synthetic biology

CA Merrick, J Zhao, SJ Rosser - ACS synthetic biology, 2018 - ACS Publications
Serine integrases catalyze precise rearrangement of DNA through site-specific
recombination of small sequences of DNA called attachment (att) sites. Unlike other site …

A mechanistic model of the BLADE platform predicts performance characteristics of 256 different synthetic DNA recombination circuits

JE Bowyer, C Ding, BH Weinberg… - PLoS Computational …, 2020 - journals.plos.org
Boolean logic and arithmetic through DNA excision (BLADE) is a recently developed
platform for implementing inducible and logical control over gene expression in mammalian …

Low-burden biological feedback controllers for near-perfect adaptation

H Steel, A Papachristodoulou - ACS synthetic biology, 2019 - ACS Publications
The robustness and reliability of synthetic biological systems can be substantially improved
by the introduction of feedback control architectures that parallel those employed in …

Design and implementation of feedback control systems for synthetic biology

H Steel - 2019 - ora.ox.ac.uk
Synthetic biology is a growing field at the interface of the engineering and biological
sciences which aims to apply rational engineering design principles in biological contexts. It …