[PDF][PDF] Pharmacologic vitreolysis

J Sebag - Retina, 1998 - vmrinstitute.com
800 reorganization of vitreous macromolecules resulting in gel liquefaction and structural
changes that destabilize the vitreous body. Molecular changes at the vitreoretinal interface …

Vitreous antioxidants, degeneration, and vitreo-retinopathy: exploring the links

E Ankamah, J Sebag, E Ng, JM Nolan - Antioxidants, 2019 - mdpi.com
The transparent vitreous body, which occupies about 80% of the eye's volume, is laden with
numerous enzymatic and non-enzymatic antioxidants that could protect the eye from …

The vitreous gel: more than meets the eye

NM Holekamp - American journal of ophthalmology, 2010 - Elsevier
PURPOSE: To reexamine the role of the vitreous gel in ocular health and disease based on
recent information in the ophthalmic literature. DESIGN: Perspective. METHODS: Review …

[HTML][HTML] Molecular biology of pharmacologic vitreolysis

J Sebag - Transactions of the American Ophthalmological Society, 2005 - ncbi.nlm.nih.gov
Purpose Pharmacologic vitreolysis is a promising new therapy to improve vitreoretinal
surgery and, ultimately, prevent disease by mitigating the contribution of vitreous to …

Internal limiting membrane peeling in vitreo-retinal surgery

E Abdelkader, N Lois - Survey of ophthalmology, 2008 - Elsevier
Peeling the internal limiting membrane of the retina has become a very common procedure
performed by vitreo-retinal surgeons. The combination of new microsurgical instrumentation …

Microplasmin-induced posterior vitreous detachment affects vitreous oxygen levels

PA Quiram, VR Leverenz, RM Baker, L Dang, FJ Giblin… - Retina, 2007 - journals.lww.com
Purpose: To determine if enzymatic induction of a posterior vitreous detachment (PVD)
and/or vitreous liquefaction affects O 2 concentration in the vitreous cavity in animals with …

Emerging nonsurgical methods for the treatment of vitreomacular adhesion: a review

EW Schneider, MW Johnson - Clinical Ophthalmology, 2011 - Taylor & Francis
With the dissemination of optical coherence tomography over the past two decades, the role
of persistent vitreomacular adhesion (VMA) in the development of numerous macular …

Pharmacologic vitreolysis—premise and promise of the first decade

J Sebag - Retina, 2009 - journals.lww.com
The term pharmacologic vitreolysis first appeared in the world's literature one decade ago in
the pages of the journal Retina. 1 The coining of this term formalized a new field and was …

[HTML][HTML] Posterior vitreous detachment induced by nattokinase (subtilisin NAT): a novel enzyme for pharmacologic vitreolysis

A Takano, A Hirata, K Ogasawara… - … & visual science, 2006 - jov.arvojournals.org
purpose. To investigate the effects of intravitreal injection of nattokinase (subtilisin NAT), a
serine protease that is produced by Bacillus subtilis (natto), for induction of posterior vitreous …

Effects of vitreous liquefaction on the intravitreal distribution of sodium fluorescein, fluorescein dextran, and fluorescent microparticles

LE Tan, W Orilla, PM Hughes, S Tsai… - … & visual science, 2011 - iovs.arvojournals.org
Purpose.: The effects of vitreous liquefaction in the elderly on the distribution of drugs from
intravitreal injections, depots, or devices remains unclear. The purpose of the present study …