Consolidating the information that we have on pharmacogenetics and on cytokine genetics
to produce patient-oriented individualized drug regimens is an important challenge in …

Background Results from published studies on the association of donor or recipient TNF-A−
308G/A polymorphism with acute rejection (AR) of renal allograft are inconsistent. We …

Background Interleukin-10 (IL-10) is an important immunomodulatory cytokine. Several
studies focused the association between IL-10 promoter gene polymorphisms and graft …

The− 308G/A SNP of tumor necrosis factor-alpha (TNF-α) gene affects TNF‐α production. As
its impact on transplant outcome remains open to debate, we decided to genotype it in a …

BACKGROUND: Results from published studies on the association of donor or recipient IL-6–
174G/C (rs1800795) polymorphism with acute rejection (AR) of renal allograft are …

Objective Transplantation of renal grafts is an established treatment for renal failure in a
variety of medical conditions. Acute allograft rejection remains an important cause of …

The modulation of the immune system following solid organ transplantation has made
considerable progress with new immunosuppressive regimens and has considerably …

The field remains controversial because of differences in populations, study design, and
statistical methods. Studies are based on candidate gene analysis; however, genome-wide …

Objective: The aim of this study was to investigate the association between interleukin (IL)-
10-1082 (G/A) promoter polymorphism and acute rejection (AR) in renal transplant …

Introduction. Single nucleotide polymorphisms within promoter or other regulatory
sequences of cytokine genes mainly influence the level of production and secretion of …