Bioinformatic analysis of snoaL, snoaM, and snoaE genes from Streptomyces nogalater, a
microorganism producing the anthracycline antibiotic nogalamycin, is reported. The results …

Abstract Streptomyces nogalater Lv65 (= IMET 43360) is a producer of the anthracycline
antitumor antibiotic nogalamycin. In this work, some aspects of the regulation of …

为了考察基因snogE 中断对诺加霉素生物合成的影响, 比对多种糖基转移酶的氨基酸序列,
并克隆与已知蒽环类抗生素糖基转移酶序列同源性最高的snogE 编码基因片段 …

Influence of cloned regulatory genes on nogalamycin biosynthesis by Streptomyces
nogalater LV65 strain has been studied. Gene snorA from the S. nogalater genome was …

Nogalamycin is a polyketide antibiotic produced by Streptomyces nogalater Lv65. Antibiotic
is glycosylated with nogalose and nogalamine sugar moieties. Bioinformatic analysis of the …

Strains of the actinomycetes Streptomyces nogalater Lv65, S. echinatus DSM40730, and S.
peucetius subsp. caesius ATCC27952 are producers of the anthracycline antibiotics …

Nogalamycin is an anthracycline antitumor antibiotic, consisting of the aromatic aglycone
attached with a nogalose and a nogalamine. At present, the biosynthesis pathway of …

Stringent response is a pleiotropic physiological response of cells caused by deficiency of
aminoacetylated tRNAs and, correspondingly, by the arrest of protein synthesis. This …

Polyketides are a large group of structurally diverse natural products that have shown a
variety of biological activities. These molecules are synthesized by polyketide synthases …

Anthracycline antibiotics are an important group of anticancer compounds widely used in
tumor chemotherapy. They are used to treat different types of diseases such as leukemias …