Owing to the extensive prevalence of resistant bacteria to numerous antibiotic classes,
antimicrobial resistance (AMR) poses a well-known hazard to world health. As an alternate …

Objective: Efflux-mediated resistance is a growing therapeutic complication as it reduces the
efficacy of antibiotics. In gram-negative bacteria like E. coli and K. pneumoniae, this can be …

Objective: Hypoxia plays a significant role in governing many vital signalling molecules in
the central nervous system (CNS). Hypoxic exposure has also been depicted as a stimulus …

Multidrug resistance (MDR) poses a severe threat to human health. The existence of efflux
pumps primarily contributes to resistance in Gram-negative bacterial infections. Efflux pump …

Objective: Cancer is the major worldwide problem. It arises due to uncontrolled growth of
cells. In the present study, a series of novel coumarin derivatives were designed and …

Antibiotic resistance is mediated by virulence mechanisms. While genetic antibiotic
resistance can be detected by standard susceptibility assays, subpopulations of …

Objective: Naringenin is a dietary biomolecule with broad spectrum of activities which
protects neurons from various neurotoxic insults and improves cognition and motor function …

Objective: The objective of this study was to explore the therapeutic role of biomolecules in
targeting the altered expression of Parkin in PD pathogenesis. Methods: We employed …