Pancreatic ductal adenocarcinoma (PDAC) remains one of the deadliest cancers. Significant
efforts have largely defined major genetic factors driving PDAC pathogenesis and …

Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …

Survival data for pancreatic cancer are usually based on actuarial calculations and actual
long-term survival rates are rarely reported. Here we use population-level data from the …

Pancreatic cysts are very common with the majority incidentally identified. There are several
types of pancreatic cysts; some types can contain cancer or have malignant potential …

Pancreatic cancer is the deadliest disease, with a five-year overall survival rate of just 11%.
The pancreatic cancer patients diagnosed with early screening have a median overall …

Pancreatic cancer, a highly aggressive tumour type with uniformly poor prognosis,
exemplifies the classically held view of stepwise cancer development. The current model of …

Importance Pancreatic cancer is an uncommon cancer with an age-adjusted annual
incidence of 12.9 cases per 100 000 person-years. However, the death rate is 11.0 deaths …

Pancreatic cancer is one of our most lethal malignancies. Despite substantial improvements
in the survival rates for other major cancer forms, pancreatic cancer survival rates have …

Oncogenic transformation alters lipid metabolism to sustain tumor growth. We define a
mechanism by which cholesterol metabolism controls the development and differentiation of …

Despite considerable research efforts, pancreatic cancer is associated with a dire prognosis
and a 5-year survival rate of only 10%. Early symptoms of the disease are mostly …