Recent progress on polysaccharide-based hydrogels for controlled delivery of therapeutic biomolecules

MI Rial-Hermida, A Rey-Rico… - ACS Biomaterials …, 2021 - ACS Publications
A plethora of applications using polysaccharides have been developed in recent years due
to their availability as well as their frequent nontoxicity and biodegradability. These polymers …

Looking into the future: toward advanced 3D biomaterials for stem‐Cell‐based regenerative medicine

Z Liu, M Tang, J Zhao, R Chai, J Kang - Advanced Materials, 2018 - Wiley Online Library
Stem‐cell‐based therapies have the potential to provide novel solutions for the treatment of
a variety of diseases, but the main obstacles to such therapies lie in the uncontrolled …

3D bioprinting of BMSC-laden methacrylamide gelatin scaffolds with CBD-BMP2-collagen microfibers

M Du, B Chen, Q Meng, S Liu, X Zheng, C Zhang… - …, 2015 - iopscience.iop.org
Abstract Three-dimensional (3D) bioprinting combines biomaterials, cells and functional
components into complex living tissues. Herein, we assembled function-control modules into …

Toward the development of biomimetic injectable and macroporous biohydrogels for regenerative medicine

K Flégeau, R Pace, H Gautier, G Rethore… - Advances in Colloid and …, 2017 - Elsevier
Repairing or replacing damaged human tissues has been the ambitious goal of
regenerative medicine for over 25 years. One promising approach is the use of hydrated …

3D cell culture—can it Be as popular as 2D cell culture?

M Sun, A Liu, X Yang, J Gong, M Yu… - Advanced …, 2021 - Wiley Online Library
A 3D cell culture has developed rapidly in recent years, as cells growing on a flat substrate
in a static environment are far from achieving an in vivo status. Currently, researchers have …

3D bioprinting mesenchymal stem cell-derived neural tissues using a fibrin-based bioink

M Restan Perez, R Sharma, NZ Masri, SM Willerth - Biomolecules, 2021 - mdpi.com
Current treatments for neurodegenerative diseases aim to alleviate the symptoms
experienced by patients; however, these treatments do not cure the disease nor prevent …

Advances of stem cell-laden hydrogels with biomimetic microenvironment for osteochondral repair

B Xu, J Ye, FZ Yuan, JY Zhang, YR Chen… - … in Bioengineering and …, 2020 - frontiersin.org
Osteochondral damage from trauma or osteoarthritis is a general joint disease that can lead
to an increased social and economic burden in the modern society. The inefficiency of …

Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells

W Jia, X Jiang, W Liu, L Wang… - International …, 2018 - spandidos-publications.com
Abstract Three-dimensional (3D) culture has been increasingly used to investigate tumor
cell biology for improved simulation of the natural developing environment. However, the …

New scaffolds encapsulating TGF-β3/BMP-7 combinations driving strong chondrogenic differentiation

J Crecente-Campo, E Borrajo, A Vidal… - European Journal of …, 2017 - Elsevier
The regeneration of articular cartilage remains an unresolved question despite the current
access to a variety of tissue scaffolds activated with growth factors relevant to this …

Design and use of chimeric proteins containing a collagen-binding domain for wound healing and bone regeneration

C Addi, F Murschel, G De Crescenzo - Tissue Engineering Part B …, 2017 - liebertpub.com
Collagen-based biomaterials are widely used in the field of tissue engineering; they can be
loaded with biomolecules such as growth factors (GFs) to modulate the biological response …