The genetic diversity of Trypanosoma cruzi, the protozoan agent of Chagas disease, is
widely recognized. At present, T. cruzi is partitioned into seven discrete typing units (DTUs) …

Chagas disease, caused by Trypanosoma cruzi, is treated with only two drugs;
benznidazole and nifurtimox. These drugs have some disadvantages, including their …

One of the most significant health problems in the American continent in terms of human
health, and socioeconomic impact is Chagas disease, caused by the protozoan parasite …

Chagas disease is a neglected tropical disease caused by the protozoan Trypanosoma
cruzi. Currently, only nitroheterocyclic nifurtimox (NFX) and benznidazole (BNZ) are …

Human trypanosomiasis and leishmaniasis are vector‐borne neglected tropical diseases
caused by infection with the protozoan parasites Trypanosoma spp. and Leishmania spp …

Chagas disease, caused by the protozoan Trypanosoma cruzi, is a lifelong and debilitating
illness of major significance throughout Latin America and an emergent threat to global …

Background New safe and effective treatments for Chagas disease (CD) are urgently
needed. Current chemotherapy options for CD have significant limitations, including failure …

Chagas' disease is responsible for significant mortality and morbidity in Latin America.
Current treatments display variable efficacy and have adverse side effects, hence more …

Background Current chemotherapy for Chagas disease is unsatisfactory due to its limited
efficacy, particularly in the chronic phase, with frequent side effects that can lead to treatment …

Covering: 1995 to 2010 Here, we review studies that have investigated the activity of plant-
derived compounds against Trypanosoma cruzi, the etiologic agent of Chagas' disease. In …