[HTML][HTML] Perineural invasion of cancer: a complex crosstalk between cells and molecules in the perineural niche

SH Chen, BY Zhang, B Zhou, CZ Zhu… - American journal of …, 2019 - ncbi.nlm.nih.gov
Perineural invasion (PNI) can be found in a variety of malignant tumors. It is a sign of tumor
metastasis and invasion and portends the poor prognosis of patients. The pathological …

[HTML][HTML] Nerve-sparing radical hysterectomy in the precision surgery for cervical cancer

N Sakuragi, G Murakami, Y Konno… - Journal of …, 2020 - ncbi.nlm.nih.gov
Precision cancer surgery is a system that integrates the accurate evaluation of tumor
extension and aggressiveness, precise surgical maneuvers, prognosis evaluation, and …

MicroRNA-449a is downregulated in cervical cancer and inhibits proliferation, migration, and invasion

L Wang, Y Zhao, W Xiong, W Ye, W Zhao… - Oncology research and …, 2019 - karger.com
Introduction: Cervical cancer is one of the most common malignant tumors among women in
the world. MicroRNA-449a (miR-449a) has been identified as a tumor suppressor gene in …

Is perineural invasion a novel prognostic factor useful to tailor adjuvant treatment in patients treated with primary surgery for cervical and vulvar carcinoma?

A Gadducci, S Pistolesi, S Cosio… - Anticancer …, 2020 - ar.iiarjournals.org
Perineural invasion (PNI) is detected in 7.0-35.1% of cervical carcinomas. This histological
finding correlates with cervical invasion, lymph-vascular space invasion (LVSI), tumor size …

Perineural invasion (PNI) in vulvar carcinoma: a review of 421 cases

MP Salcedo, AK Sood, R Dos Reis, P Ramalingam… - Gynecologic …, 2019 - Elsevier
Objectives To evaluate the prevalence and associated prognostic indicators in patients with
vulvar carcinoma with and without evidence of perineural invasion (PNI). Methods A …

Oncological outcomes after Okabayashi-Kobayashi radical hysterectomy for early and locally advanced cervical cancer

N Sakuragi, T Kato, C Shimada, M Kaneuchi… - JAMA Network …, 2020 - jamanetwork.com
Importance The role of surgery in early-stage cervical cancer has been established, but it is
controversial in locally advanced cervical cancer. Objective To determine whether a radical …

[HTML][HTML] Perineural invasion in cervical cancer: A multicenter retrospective study

X Chen, H Duan, H Zhao, F He, L Yin, Y Liu… - European Journal of …, 2024 - Elsevier
Objective The study aimed to evaluate the accuracy of perineural invasion (PNI) diagnosis in
cervical cancer, and to analyze the impact of PNI on the prognosis and postoperative …

[HTML][HTML] CTHRC1 as a novel biomarker in the diagnosis of cervical squamous cell carcinoma

G Xu, W Fan, F Wang, H Lu, X Xing… - … Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
To verify whether the collagen triple helix repeat containing 1 (CTHRC1) can be used as a
potential biomarker in diagnosis of cervical cancer, by evaluating the expression level of …

The Diagnosis of Perineural Invasion: A Crucial Factor in Novel Algorithm of Coexistence of Conventional and Nerve-Sparing Radical Hysterectomy

A Skręt, JE Skręt-Magierło, M Książek, B Gawlik… - Diagnostics, 2021 - mdpi.com
Nerve-sparing radical hysterectomy (NSRH) was introduced to mitigate adverse effects
associated with conventional radical hysterectomy (CRH) in cervical cancer. However, the …

[PDF][PDF] Perineural invasion in early-stage cervical cancer: detection and influence on prognosis.

Y Long, D Yao, Y Wei, J Chen… - European Journal of …, 2019 - article.imrpress.com
Purpose: To compare staining methods for detecting perineural invasion (PNI) in early-stage
cervical cancer and assess the influence of PNI on survival. Materials and Methods: The …