Highlights•Syts also regulate endocytosis and vesicle trafficking, not just
exocytosis.•Neurons as well as glia employ synaptotagmins (Syts) for diverse …

Abstract N-methyl-D-aspartate (NMDA) receptor-dependent long-term potentiation (LTP)
and long-term depression (LTD) of signal transmission form neural circuits and thus are …

Abstract Autism Spectrum Disorder (ASD) is a multifaceted condition associated with
difficulties in social interaction and communication. It also shares several comorbidities with …

A mounting body of evidence suggests that prenatal inflammation may enhance the rate of
age‐associated cognitive decline and may involve aberrant amounts of synaptic proteins in …

Dietary omega‐3 fatty acids accumulate and are actively retained in central nervous system
membranes, mainly in synapses, dendrites and photoreceptors. Despite this selective …

Excitotoxicity is a common pathological process in Alzheimer's disease (AD) which is
caused by the over-activity of N-Methyl-D-Aspartate receptors (NMDARs). The release of …

Synapse is the fundamental structure for neurons to transmit information between cells. The
proper synapse formation is crucial for developing neural circuits and cognitive functions of …

The SNARE protein SNAP-25 is well documented as regulator of presynaptic vesicle
exocytosis. Increasing evidence suggests roles for SNARE proteins in postsynaptic …

Age-associated impairment of spatial learning and memory (AISLM) presents substantial
challenges to our health and society. Increasing evidence has indicated that embryonic …

Traumatic brain injury (TBI) is a public health concern, with an estimated 42 million cases
globally every year. The majority of TBIs are mild TBIs, also known as concussion, and result …