Astrocytes in functional recovery following central nervous system injuries
Astrocytes are increasingly recognised as partaking in complex homeostatic mechanisms
critical for regulating neuronal plasticity following central nervous system (CNS) insults …
critical for regulating neuronal plasticity following central nervous system (CNS) insults …
Engineered cell culture microenvironments for mechanobiology studies of brain neural cells
L Castillo Ransanz, PFJ Van Altena… - … in bioengineering and …, 2022 - frontiersin.org
The biomechanical properties of the brain microenvironment, which is composed of different
neural cell types, the extracellular matrix, and blood vessels, are critical for normal brain …
neural cell types, the extracellular matrix, and blood vessels, are critical for normal brain …
Polarized focal adhesion kinase activity within a focal adhesion during cell migration
Focal adhesion kinase (FAK) relays integrin signaling from outside to inside cells and
contributes to cell adhesion and motility. However, the spatiotemporal dynamics of FAK …
contributes to cell adhesion and motility. However, the spatiotemporal dynamics of FAK …
Integrin signaling in the central nervous system in animals and human brain diseases
H Ikeshima-Kataoka, C Sugimoto… - International journal of …, 2022 - mdpi.com
The integrin family is involved in various biological functions, including cell proliferation,
differentiation and migration, and also in the pathogenesis of disease. Integrins are …
differentiation and migration, and also in the pathogenesis of disease. Integrins are …
Transcriptomic and morphological maturation of human astrocytes in cerebral organoids
M Verkerke, A Berdenis van Berlekom, V Donega… - Glia, 2024 - Wiley Online Library
Cerebral organoids (CerOrgs) derived from human induced pluripotent stem cells (iPSCs)
are a valuable tool to study human astrocytes and their interaction with neurons and …
are a valuable tool to study human astrocytes and their interaction with neurons and …
Thy-1-Integrin Interactions in cis and Trans Mediate Distinctive Signaling
Thy-1 is a cell surface glycosylphosphatidylinositol (GPI)-anchored glycoprotein that bears a
broad mosaic of biological roles across various cell types. Thy-1 displays strong …
broad mosaic of biological roles across various cell types. Thy-1 displays strong …
Thy-1 (CD90)-regulated cell adhesion and migration of mesenchymal cells: insights into adhesomes, mechanical forces, and signaling pathways
Cell adhesion and migration depend on the assembly and disassembly of adhesive
structures known as focal adhesions. Cells adhere to the extracellular matrix (ECM) and …
structures known as focal adhesions. Cells adhere to the extracellular matrix (ECM) and …
Magnetogenetics as a promising tool for controlling cellular signaling pathways
Magnetogenetics emerges as a transformative approach for modulating cellular signaling
pathways through the strategic application of magnetic fields and nanoparticles. This …
pathways through the strategic application of magnetic fields and nanoparticles. This …
Proteoglycans in mechanobiology of tissues and organs: Normal functions and mechanopathology
MC Farach‐Carson, D Wu… - Proteoglycan Research, 2024 - Wiley Online Library
Proteoglycans (PGs) are a diverse class of glycoconjugates that serve critical functions in
normal mechanobiology and mechanopathology. Both the protein cores and attached …
normal mechanobiology and mechanopathology. Both the protein cores and attached …
Thy-1-integrin interactions in cis and trans mediate distinctive signaling
Thy-1 is a cell surface glycosylphosphatidylinositol (GPI)-anchored glycoprotein that bears a
broad mosaic of biological roles across various cell types. Thy-1 displays strong …
broad mosaic of biological roles across various cell types. Thy-1 displays strong …