Discontinuation, suboptimal adherence, and reinitiation of oral HIV pre-exposure prophylaxis: a global systematic review and meta-analysis

J Zhang, C Li, J Xu, Z Hu, SE Rutstein, JD Tucker… - The lancet HIV, 2022 - thelancet.com
Background Poor adherence to oral HIV pre-exposure prophylaxis (PrEP) diminishes its
clinical and public health benefits. This study synthesises evidence regarding …

The future of HIV pre-exposure prophylaxis adherence: reducing barriers and increasing opportunities

JE Haberer, A Mujugira, KH Mayer - The Lancet HIV, 2023 - thelancet.com
The effectiveness of HIV pre-exposure prophylaxis (PrEP) hinges on adherence, which has
been restricted by multifaceted barriers. Uptake of PrEP has been impeded by poor access …

Real-world effectiveness of pre-exposure prophylaxis in men at high risk of HIV infection in France: a nested case-control study

H Jourdain, SB de Gage, D Desplas… - The Lancet Public …, 2022 - thelancet.com
Summary Background Pre-exposure prophylaxis (PrEP) has shown high efficacy in clinical
trials, but few observational studies have confirmed its effectiveness when prescribed in real …

Randomized controlled trial of a mobile health intervention to promote retention and adherence to preexposure prophylaxis among young people at risk for human …

AY Liu, E Vittinghoff, P von Felten… - Clinical Infectious …, 2019 - academic.oup.com
Background Young men who have sex with men are among the most vulnerable to human
immunodeficiency virus (HIV) infection. Although preexposure prophylaxis (PrEP) has …

Barriers and facilitators of PrEP adherence for young men and transgender women of color

S Wood, R Gross, JA Shea, JA Bauermeister… - AIDS and Behavior, 2019 - Springer
We aimed to discover barriers and facilitators of HIV pre-exposure prophylaxis (PrEP)
adherence in young men and transgender women of color who have sex with men …

Persistence on HIV preexposure prophylaxis medication over a 2‐year period among a national sample of 7148 PrEP users, United States, 2015 to 2017

KC Coy, RJ Hazen, HS Kirkham… - Journal of the …, 2019 - Wiley Online Library
Introduction Persistence on preexposure prophylaxis for HIV prevention (PrEP) medication
has rarely been reported for periods greater than one year, or in real‐world settings. This …

[HTML][HTML] Preexposure prophylaxis for prevention of HIV acquisition among adolescents: clinical considerations, 2020

MR Tanner - MMWR. Recommendations and Reports, 2020 - cdc.gov
Preexposure prophylaxis (PrEP) with antiretroviral medication has been proven effective in
reducing the risk for acquiring human immunodeficiency virus (HIV). The fixed-dose …

Patterns and clinical consequences of discontinuing HIV preexposure prophylaxis during primary care

D Krakower, KM Maloney, VE Powell… - Journal of the …, 2019 - Wiley Online Library
Introduction Discontinuations of HIV preexposure prophylaxis (Pr EP) by at‐risk individuals
could decrease the effectiveness of Pr EP. Our objective was to characterize patterns of …

HIV prevention interventions for adolescents

S Hosek, A Pettifor - Current HIV/AIDS Reports, 2019 - Springer
Abstract Purpose of Review The goal of this paper is to review recent data on biomedical,
behavioral, and structural HIV prevention interventions for adolescents and young adults …

Initiation, discontinuation, and restarting HIV pre-exposure prophylaxis: ongoing implementation strategies

SE Rutstein, DK Smith, S Dalal, RC Baggaley… - The lancet HIV, 2020 - thelancet.com
When used appropriately, pre-exposure prophylaxis (PrEP) substantially reduces the risk of
HIV acquisition. Early implementation outcomes often suggest poor PrEP adherence and …