Classification and pathogenesis of cerebral hemorrhages after thrombolysis in ischemic stroke
P Trouillas, R von Kummer - Stroke, 2006 - Am Heart Assoc
Background and Purpose—Brain hemorrhage after ischemic stroke is a serious
complication of treatment; however, its pathology is poorly understood. A classification …
complication of treatment; however, its pathology is poorly understood. A classification …
Hemorrhagic transformation: a review of the rate of hemorrhage in the major clinical trials of acute ischemic stroke
ES Sussman, ES Connolly Jr - Frontiers in neurology, 2013 - frontiersin.org
Acute ischemic stroke is a devastating disease that is often complicated by hemorrhagic
transformation. While significant advances have been made over the past two decades with …
transformation. While significant advances have been made over the past two decades with …
The Heidelberg bleeding classification: classification of bleeding events after ischemic stroke and reperfusion therapy
2982 Stroke October 2015 threshold between PH1 and PH2 was not clarified. 10
Regardless, in the ECASS, only PH2, but not PH1 or HI, was associated with early …
Regardless, in the ECASS, only PH2, but not PH1 or HI, was associated with early …
Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke: the European Cooperative Acute Stroke Study (ECASS)
Objective.—To evaluate the efficacy and safety of intravenous thrombolysis using
recombinant tissue plasminogen activator (rt-PA) in patients with acute ischemic stroke …
recombinant tissue plasminogen activator (rt-PA) in patients with acute ischemic stroke …
'Malignant'middle cerebral artery territory infarction: clinical course and prognostic signs
W Hacke, S Schwab, M Horn, M Spranger… - Archives of …, 1996 - jamanetwork.com
Background: Although the clinical features of space-occupying ischemic stroke are well
known, there are limited prospective data on the clinical course of complete middle cerebral …
known, there are limited prospective data on the clinical course of complete middle cerebral …
Hemorrhagic transformation within 36 hours of a cerebral infarct: relationships with early clinical deterioration and 3-month outcome in the European Cooperative …
M Fiorelli, S Bastianello, R von Kummer, GJ del Zoppo… - Stroke, 1999 - Am Heart Assoc
Background and Purpose—The clinical correlates of the varying degrees of early
hemorrhagic transformation of a cerebral infarct are unclear. We investigated the cohort of a …
hemorrhagic transformation of a cerebral infarct are unclear. We investigated the cohort of a …
Early hemorrhagic transformation of brain infarction: rate, predictive factors, and influence on clinical outcome: results of a prospective multicenter study
Background and Purpose—Early hemorrhagic transformation (HT) is a complication of
ischemic stroke but its effect on patient outcome is unclear. The aims of this study were to …
ischemic stroke but its effect on patient outcome is unclear. The aims of this study were to …
Hemorrhagic transformation of ischemic brain tissue: asymptomatic or symptomatic?
C Berger, M Fiorelli, T Steiner, WR Schäbitz… - Stroke, 2001 - Am Heart Assoc
Background and Purpose—The term symptomatic hemorrhage secondary to ischemic stroke
implies a clear causal relationship between clinical deterioration and hemorrhagic …
implies a clear causal relationship between clinical deterioration and hemorrhagic …
Matrix metalloproteinase-9 pretreatment level predicts intracranial hemorrhagic complications after thrombolysis in human stroke
J Montaner, CA Molina, J Monasterio, S Abilleira… - Circulation, 2003 - Am Heart Assoc
Background—Matrix metalloproteinase (MMP) expression is related to blood brain barrier
disruption after cerebral ischemia. Moreover, MMP inhibitors reduce hemorrhagic …
disruption after cerebral ischemia. Moreover, MMP inhibitors reduce hemorrhagic …
Early blood–brain barrier disruption in human focal brain ischemia
Loss of integrity of the blood–brain barrier (BBB) resulting from ischemia/reperfusion is
believed to be a precursor to hemorrhagic transformation (HT) and poor outcome. We used …
believed to be a precursor to hemorrhagic transformation (HT) and poor outcome. We used …