Phenoconversion is a phenomenon that converts genotypic extensive metabolizers (EM s)
into phenotypic poor metabolizers (PM s) of drugs, thereby modifying their clinical response …

Wider use of oral anticoagulants has led to an increasing frequency of warfarin-related
intracerebral hemorrhage (ICH). The high early mortality of approximately 50% has …

Objective: To define temporal trends in the incidence of anticoagulant-associated
intracerebral hemorrhage (AAICH) during the 1990s and relate them to rates of …

BACKGROUND: The risk of falls is the most commonly cited reason for not providing oral
anticoagulation, although the risk of bleeding associated with falls on oral anticoagulants is …

Background: Anticoagulants and antiplatelet drugs (eg, warfarin, clopidogrel and
acetylsalicylic acid) are key therapeutic agents in the treatment of cardiovascular diseases …

Background and purpose Develop and validate a contemporary bleeding risk model to
guide the clinical use of warfarin in the elderly atrial fibrillation (AF) population. Methods …

The association of CYP2C9 and VKORC1 1173C/T genotype and risk of hemorrhage
among African Americans and European Americans is presented. This association was …

Methods: We conducted a hospital-based casecontrol study at the Kantonsspital Winterthur,
encompassing 74 patients with a first-time GI bleeding in the year 2005 and 148 controls …

Background Long-term predictors and causes of death are understudied in elderly patients
with acute venous thromboembolism. Methods We prospectively followed up 991 patients …

Background and Purpose—Warfarin use has rapidly increased with the aging of the
population. We investigated the temporal trends in the incidence and outcome of warfarin …