Despite advances in critical care medicine, infection remains a significant problem that continues to be complicated with the challenge of antibiotic resistance …
P Mertowska, K Smolak, S Mertowski… - International journal of …, 2023 - mdpi.com
Interferons are a group of immunomodulatory substances produced by the human immune system in response to the presence of pathogens, especially during viral and bacterial …
AM Owen, L Luan, KR Burelbach, MA McBride… - Frontiers in …, 2022 - frontiersin.org
Immunocompromised populations are highly vulnerable to developing life-threatening infections. Strategies to protect patients with weak immune responses are urgently needed …
Inflammatory bowel disease lacks a long-lasting and broadly effective therapy. Here, by taking advantage of the anti-infection and anti-inflammatory properties of natural antibodies …
Highlights•Studies suggest adjuvants could induce epigenetic reprogramming of myeloid cells.•Reprogramming could lead to a durable state of heightened antiviral resistance.•This …
K Matsumoto, H Yasuoka, K Yoshimoto, K Suzuki… - Scientific reports, 2021 - nature.com
Neutrophils form neutrophil extracellular traps (NETs), which are involved in the pathogenesis of ANCA-associated vasculitis (AAV). Recent reports suggest that platelets …
While the efficacy of many current vaccines is well-established, various factors can diminish their effectiveness, particularly in vulnerable groups. Amidst emerging pandemic threats …
JY Fan, Y Huang, Y Li, TA Muluh, SZ Fu… - Cancer …, 2022 - Wiley Online Library
Tumors are presently a major threat to human life and health. Malignant tumors are conventionally treated through radiotherapy and chemotherapy. However, traditional …
CS Yang, CM Coopersmith, JD Lyons - Frontiers in Immunology, 2024 - frontiersin.org
Cell death proteins play a central role in host immune signaling during sepsis. These interconnected mechanisms trigger cell demise via apoptosis, necroptosis, and pyroptosis …