Semaphorins, originally discovered as guidance cues for developing axons, are involved in
many processes that shape the nervous system during development, from neuronal …

Chronic pain is a debilitating condition that influences the social, economic, and
psychological aspects of patients' lives. Hence, the need for better treatment is drawing …

Macroautophagy/autophagy is generally regarded as a cytoprotective mechanism, and it
remains a matter of controversy whether autophagy can cause cell death in mammals. Here …

Extracellular vesicles (EVs) have emerged as mediators of cellular communication, in part
via the delivery of associated microRNAs (miRNAs), small non-coding RNAs that regulate …

Stem cell dysfunction drives many age-related disorders. Identifying mechanisms that
initially compromise stem cell behavior represent early targets to promote tissue function …

Neurons migrate from their birthplaces to the destinations, and extending axons navigate to
their synaptic targets by sensing various extracellular cues in spatiotemporally controlled …

Glycosylphosphatidylinositol (GPI)-anchored proteins are a specialized class of lipid-
associated neuronal membrane proteins that perform diverse functions in the dynamic …

Semaphorins are a family originally identified as axonal guidance molecules. They are also
involved in tumor growth, angiogenesis, immune regulation, as well as other biological and …

Interplay between embryonic enteric neural stem cells (ENSCs) and enteric mesenchymal
cells (EMCs) in the embryonic gut is essential for normal development of the enteric nervous …

Adult neurogenesis is the process by which neural stem cells give rise to new functional
neurons in specific regions of the adult brain, a process that occurs throughout life …