The discovery of genotype 16 as the prototype oncogenic human papillomavirus (HPV)
initiated a quarter century of laboratory and epidemiological studies that demonstrated their …

The capsid protein L2 plays major roles in both papillomavirus assembly and the infectious
process. While L1 forms the majority of the capsid and can self-assemble into empty virus …

Cervical cancer is caused by human papillomavirus infection. Most human papillomavirus
infection is harmless and clears spontaneously but persistent infection with high-risk human …

Human papillomavirus (HPV) is the necessary cause of cervical cancer, the fourth most
common cancer and cause of cancer-related death in females worldwide. HPV also causes …

As compared with peptide-or protein-based vaccines, naked DNA vectors and even
traditional attenuated or inactivated virus vaccines, virus-like particles (VLPs) are an …

Cervical cancer continues to be the second largest cause of cancer deaths in women
worldwide. Persistent infection with high-risk types of human papillomavirus (HPV) is a …

Simple Summary Cervical cancer is the fourth most common cancer in women worldwide.
Tumour-related deaths are most frequent in low-and middle-income countries. Currently …

A wealth of evidence has led to the conclusion that virtually all cases of cervical cancer are
attributable to persistent infection by a subset of human papillomavirus (HPV) types …

Since the discovery of the causal association between human papillomavirus (HPV) and
cervical cancer, efforts to develop an effective prophylactic vaccine to prevent high-risk HPV …

Pseudovirions of human papillomavirus type 16 (HPV16), the principal etiologic agent in
50% of cervical cancers, were used as a model system to investigate the cell surface …