Tissue engineering (TE) is the approach to combine cells with scaffold materials and
appropriate growth factors to regenerate or replace damaged or degenerated tissue or …

Collagen is the oldest and most abundant extracellular matrix protein that has found many
applications in food, cosmetic, pharmaceutical, and biomedical industries. First, an overview …

Despite considerable advances in microsurgical techniques over the past decades, bone
tissue remains a challenging arena to obtain a satisfying functional and structural restoration …

Bone is consisted of bone matrix, cells and bioactive factors, and bone matrix is the
combination of inorganic minerals and organic polymers. Type I collagen fibril made of five …

Extracellular matrix (ECM) derived components are emerging sources for the engineering of
biomaterials that are capable of inducing desirable cell-specific responses. This review …

The combined potential of hydrogels and rapid prototyping technologies has been an
exciting route in developing tissue engineering scaffolds for the past decade. Hydrogels …

The development of responsive biomaterials capable of demonstrating modulated function
in response to dynamic physiological and mechanical changes in vivo remains an important …

In the literature there are conflicting reports on the optimal scaffold mean pore size required
for successful bone tissue engineering. This study set out to investigate the effect of mean …

Mean pore size is an essential aspect of scaffolds for tissue-engineering. If pores are too
small cells cannot migrate in towards the center of the construct limiting the diffusion of …

Engineering biomaterials that mimic the extracellular matrix (ECM) of bone is of significant
importance since most of the outstanding properties of the bone are due to matrix …