Paracrine factors released by stem cells of mesenchymal origin and their effects in cardiovascular disease: a systematic review of pre-clinical studies

NS Mabotuwana, L Rech, J Lim, SA Hardy… - Stem cell reviews and …, 2022 - Springer
Mesenchymal stem cell (MSC) therapy has gained significant traction in the context of
cardiovascular repair, and have been proposed to exert their regenerative effects via the …

Recent advances in pre-conditioned mesenchymal stem/stromal cell (MSCs) therapy in organ failure; a comprehensive review of preclinical studies

MS Kahrizi, E Mousavi, A Khosravi, S Rahnama… - Stem cell research & …, 2023 - Springer
Mesenchymal stem/stromal cells (MSCs)‐based therapy brings the reassuring capability to
regenerative medicine through their self‐renewal and multilineage potency. Also, they …

Genetic enhancement: an avenue to combat aging-related diseases

Y Cai, Z Ji, S Wang, W Zhang, J Qu, JCI Belmonte… - Life …, 2022 - academic.oup.com
Aging is a major risk factor for multiple diseases, including cardiovascular diseases,
neurodegenerative disorders, osteoarthritis, and cancer. It is accompanied by the …

Modifying strategies for SDF-1/CXCR4 interaction during mesenchymal stem cell transplantation

Q Jiang, K Huang, F Lu, S Deng, Z Yang… - General Thoracic and …, 2022 - Springer
Mesenchymal stem cell (MSC) transplantation is regarded as a promising candidate for the
treatment of ischaemic heart disease. The major hurdles for successful clinical translation of …

[HTML][HTML] Engineering mesenchymal stem cells for premature ovarian failure: Overcoming challenges and innovating therapeutic strategies

Z Yuan, Y Zhang, X He, X Wang, X Wang, S Ren… - …, 2024 - pmc.ncbi.nlm.nih.gov
Premature ovarian failure (POF) is a leading cause of infertility in women, causing significant
psychological and physical distress. Current therapeutic options are limited, necessitating …

Effect of resveratrol and mesenchymal stem cell monotherapy and combined treatment in management of osteoporosis in ovariectomized rats: role of SIRT1/FOXO3a …

MM Elseweidy, SE El-Swefy, MA Shaheen… - Archives of Biochemistry …, 2021 - Elsevier
Osteoporosis is a skeletal disorder that is common in postmenopausal women. It is
characterized by deteriorated bone mass and microarchitecture. In this study, we aimed to …

Atf3 coordinates the survival and proliferation of cardiac macrophages and protects against ischemia–reperfusion injury

Y Shao, Y Li, Y Liu, S Zhu, J Wu, K Ma, G Li… - Nature Cardiovascular …, 2024 - nature.com
Cardiac resident MerTK+ macrophages exert multiple protective roles after ischemic injury;
however, the mechanisms regulating their fate are not fully understood. In the present study …

Stem cell therapy for cardiac regeneration: past, present, and future

JK Gill, SK Rehsia, E Verma, N Sareen… - Canadian Journal of …, 2024 - cdnsciencepub.com
Cardiac disorders remain the leading cause of mortality worldwide. Current clinical
strategies, including drug therapy, surgical interventions, and organ transplantation offer …

Long noncoding RNA repressor of adipogenesis negatively regulates the adipogenic differentiation of mesenchymal stem cells through the hnRNP A1‐PTX3‐ERK …

Y Pan, Z Xie, S Cen, M Li, W Liu, S Tang… - Clinical and …, 2020 - Wiley Online Library
Abstract Background Mesenchymal stem cells (MSCs) are pluripotent stem cells that can
differentiate via osteogenesis and adipogenesis. The mechanism underlying MSC lineage …

Gas6/AXL pathway: immunological landscape and therapeutic potential

X Zhai, D Pu, R Wang, J Zhang, Y Lin, Y Wang… - Frontiers in …, 2023 - frontiersin.org
Cancer is a disease with ecological and evolutionary unity, which seriously affects the
survival and quality of human beings. Currently, many reports have suggested Gas6 plays …