Comparative effects of domain-specific human monoclonal antibodies against LGI1 on neuronal excitability

J Sell, V Rahmati, M Kempfer, SR Irani… - Neurology …, 2023 - AAN Enterprises
Background and Objectives Autoantibodies to leucine-rich glioma inactivated protein 1
(LGI1) cause an autoimmune limbic encephalitis with frequent focal seizures and …

Monitoring of activity-driven trafficking of endogenous synaptic proteins through proximity labeling

C Pascual-Caro, J de Juan-Sanz - PLoS biology, 2024 - journals.plos.org
To enable transmission of information in the brain, synaptic vesicles fuse to presynaptic
membranes, liberating their content and exposing transiently a myriad of vesicular …

LGI1 Autoantibodies Enhance Synaptic Transmission by Presynaptic Kv1 Loss and Increased Action Potential Broadening

A Ritzau-Jost, F Gsell, J Sell, S Sachs… - Neurology …, 2024 - neurology.org
Background and Objectives Autoantibodies against the protein leucine-rich glioma
inactivated 1 (LGI1) cause the most common subtype of autoimmune encephalitis with …

An expanded palette of bright and photostable organellar Ca2+ sensors

A Moret, H Farrants, R Fan, K Zingg, CE Gee… - bioRxiv, 2025 - biorxiv.org
The use of fluorescent sensors for functional imaging has revolutionized the study of
organellar Ca2+ signaling. However, understanding the dynamic interplay between …

Developmental transcriptional control of mitochondrial homeostasis is required for activity-dependent synaptic connectivity

I Mohylyak, M Bengochea, C Pascual-Caro, N Asfogo… - bioRxiv, 2023 - biorxiv.org
During neuronal circuit formation, local control of axonal organelles ensures proper synaptic
connectivity. Whether this process is genetically encoded is unclear and if so, its …