A review of progress in single particle tracking: from methods to biophysical insights

C Manzo, MF Garcia-Parajo - Reports on progress in physics, 2015 - iopscience.iop.org
Optical microscopy has for centuries been a key tool to study living cells with minimum
invasiveness. The advent of single molecule techniques over the past two decades has …

Exosomes: mechanisms of uptake

KJ McKelvey, KL Powell, AW Ashton… - Journal of …, 2015 - journals.sagepub.com
Exosomes are 30–100 nm microvesicles which contain complex cellular signals of RNA,
protein and lipids. Because of this, exosomes are implicated as having limitless therapeutic …

Mean square displacement analysis of single-particle trajectories with localization error: Brownian motion in an isotropic medium

X Michalet - Physical Review E—Statistical, Nonlinear, and Soft …, 2010 - APS
We examine the capability of mean square displacement (MSD) analysis to extract reliable
values of the diffusion coefficient D of a single particle undergoing Brownian motion in an …

Adenovirus entry: from infection to immunity

UF Greber, JW Flatt - Annual review of virology, 2019 - annualreviews.org
More than 80 different adenovirus (AdV) types infect humans through the respiratory, ocular,
or gastrointestinal tracts. They cause acute clinical mani-festations or persist under humoral …

Dynamics of exosome internalization and trafficking

T Tian, YL Zhu, FH Hu, YY Wang… - Journal of cellular …, 2013 - Wiley Online Library
Cells release exosomes into extracellular medium. Although the important roles of
exosomes in many physiological and pathological processes are being revealed, the …

Probing cellular events, one quantum dot at a time

F Pinaud, S Clarke, A Sittner, M Dahan - Nature methods, 2010 - nature.com
Monitoring the behavior of single molecules in living cells is a powerful approach to
investigate the details of cellular processes. Owing to their optical, chemical and …

Single-particle diffusional fingerprinting: A machine-learning framework for quantitative analysis of heterogeneous diffusion

HD Pinholt, SSR Bohr, JF Iversen… - Proceedings of the …, 2021 - National Acad Sciences
Single-particle tracking (SPT) is a key tool for quantitative analysis of dynamic biological
processes and has provided unprecedented insights into a wide range of systems such as …

Innate immunity to adenovirus

R Hendrickx, N Stichling, J Koelen, L Kuryk… - Human gene …, 2014 - liebertpub.com
Human adenoviruses are the most widely used vectors in gene medicine, with applications
ranging from oncolytic therapies to vaccinations, but adenovirus vectors are not without side …

Classification of diffusion modes in single-particle tracking data: Feature-based versus deep-learning approach

P Kowalek, H Loch-Olszewska, J Szwabiński - Physical Review E, 2019 - APS
Single-particle trajectories measured in microscopy experiments contain important
information about dynamic processes occurring in a range of materials including living cells …

Classification and segmentation of nanoparticle diffusion trajectories in cellular micro environments

T Wagner, A Kroll, CR Haramagatti, HG Lipinski… - PloS one, 2017 - journals.plos.org
Darkfield and confocal laser scanning microscopy both allow for a simultaneous observation
of live cells and single nanoparticles. Accordingly, a characterization of nanoparticle uptake …