A markedly reduced interest or pleasure in activities previously considered pleasurable is a
main symptom in mood disorder and psychosis and is often present in other psychiatric …

The reproducibility crisis (or replication crisis) in biomedical research is a particularly
existential and under-addressed issue in the field of behavioral neuroscience, where, in …

Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

Measuring Behaviour is the established go-to text for anyone interested in scientific methods
for studying the behaviour of animals or humans. It is widely used by students, teachers and …

Handling can stimulate stress and anxiety in laboratory animals that negatively impacts
welfare and introduces a confounding factor in many areas of research. Picking up mice by …

The sucrose preference test (SPT) measures the relative preference of sucrose over water to
assess hedonic behaviors in rodents. Yet, it remains uncertain to what extent the SPT …

Handling is a well-known source of stress to laboratory animals and can affect variability of
results and even compromise animal welfare. The conventional tail handling in mice has …

Simple Summary Scientists use animal models to study the mechanisms of human diseases
and find new drugs to treat them. Chronic Unpredictable Mild Stress is the best animal …

Simple Summary Environmental enrichment has been widely studied with laboratory
rodents, but there is no consensus regarding what counts as enrichment or what it should …

Behavioral tests have three key elements:(1) a motivating factor (what motivates the animal
in the test);(2) an observable behavior (which behaviors we may expect the animal exhibits …