Feline mammary carcinoma (FMC) is a common aggressive malignancy with a low survival
rate that lacks viable therapeutic options beyond mastectomy. Recently, increasing efforts …

In this mini review the status, advantages, and disadvantages of large animal modeling of
breast cancer (BC) will be discussed. While most older studies of large animal BC models …

Tumor microenvironment has gained great relevance due to its ability to regulate distinct
checkpoints mediators, orchestrating tumor progression. Serum programmed cell death …

Objectives Although feline mammary carcinomas (FMCs) are highly metastatic, the literature
and treatment options pertaining to advanced tumours are scarce. This study aimed to …

Despite clinical successes in the treatment of some early stage cancers, it is undeniable that
novel and innovative approaches are needed to aid in the fight against cancer. Targeted …

ABSTRACT DNA-based vaccination is a promising approach to cancer immunotherapy.
DNA-based vaccines specific for tumor-associated antigens (TAAs) are indeed relatively …

Simple Summary Reproduction in small animals is an expanding research area, with focus
on breeding improvement and clinical management of domestic carnivores. The aim of the …

Background The receptor CXCR4 and its ligand CXCL12 play crucial roles in breast cancer.
Despite the fact that the spontaneous feline mammary carcinoma (FMC) is considered a …

Ninety percent of deaths from cancer are caused by metastasis. miRNAs are critical players
in biological processes such as proliferation, metastasis, apoptosis, and self-renewal. We …

Traditional laboratory model organisms are indispensable for cancer research and have
provided insight into numerous mechanisms that contribute to cancer development and …