Various brain-eating amoebae: the protozoa, the pathogenesis, and the disease

H Zhang, X Cheng - Frontiers of medicine, 2021 - Springer
Among various genera of free-living amoebae prevalent in nature, some members are
identified as causative agents of human encephalitis, in which Naegleria fowleri followed by …

Prevalence of free-living amoebae in swimming pools and recreational waters, a systematic review and meta-analysis

BJM Chaúque, DL Dos Santos, D Anvari, MB Rott - Parasitology Research, 2022 - Springer
Free-living amoebae (FLA) are cosmopolitan microorganisms known to be pathogenic to
humans who often have a history of contact with contaminated water. Swimming pools and …

Food-and vector-borne parasitic zoonoses: global burden and impacts

MS Hossain, T Hatta, SS Labony, KD Kwofie… - Advances in …, 2023 - Elsevier
Around 25% of the global population suffer from one or more parasitic infections, of which
food-and vector-borne parasitic zoonotic diseases are a major concern. Additionally …

Applications of medicinal chemistry for drug discovery against Acanthamoeba infections

U Ahmed, A Anwar, SK Ong, A Anwar… - Medicinal Research …, 2022 - Wiley Online Library
Acanthamoeba is a genus of free‐living amoebae, pervasively found in the environment.
Most of its pathogenic species are the causative agent of sight‐threatening Acanthamoeba …

Anti-Acanthamoeba synergistic effect of chlorhexidine and Garcinia mangostana extract or α-mangostin against Acanthamoeba triangularis trophozoite and cyst …

S Sangkanu, W Mitsuwan, W Mahabusarakam… - Scientific reports, 2021 - nature.com
Acanthamoeba spp. can cause amoebic keratitis (AK). Chlorhexidine is effective for AK
treatment as monotherapy, but with a relative failure on drug bioavailability in the deep …

Oral miltefosine as salvage therapy for refractory acanthamoeba keratitis

P Thulasi, HN Saeed, CJ Rapuano, JH Hou… - American journal of …, 2021 - Elsevier
Purpose To report a case series of patients with treatment-resistant Acanthamoeba keratitis
(AK) using oral miltefosine, often as salvage therapy. Design Descriptive, retrospective …

Photolysis of sodium chloride and sodium hypochlorite by ultraviolet light inactivates the trophozoites and cysts of Acanthamoeba castellanii in the water matrix

BJM Chaúque, MB Rott - Journal of Water and Health, 2021 - iwaponline.com
The present study aimed to investigate an effective, sustainable and accessible way to
inactivate chlorine-resistant microorganisms, such as Acanthamoeba castellanii, through the …

Molecular characterisation and potential pathogenicity analysis of Acanthamoeba isolated from recreational lakes in Peninsular Malaysia

R Abdul Halim, RH Mohd Hussain… - Journal of water and …, 2023 - iwaponline.com
The present study aims to identify the Acanthamoeba genotypes and their pathogenic
potential in three recreational lakes in Malaysia. Thirty water samples were collected by …

Phragmites australis (Cav.) Trin. ex Steud. Extract Induces Apoptosis-like Programmed Cell Death in Acanthamoeba castellanii Trophozoites

HG Lê, JS Choi, BS Hwang, YT Jeong, JM Kang, TC Võ… - Plants, 2022 - mdpi.com
Acanthamoeba keratitis (AK) is an infectious ocular disease which is difficult to diagnose
correctly and cure. Development of an effective and safe therapeutic drug for AK is needed …

Acanthamoeba species isolated from marine water in Malaysia exhibit distinct genotypes and variable physiological properties

RH Mohd Hussain, MK Abdul Ghani… - Journal of Water and …, 2022 - iwaponline.com
The present study identifies the Acanthamoeba genotypes and their pathogenic potential in
five marine waters in Malaysia. Fifty water samples were collected between January and …