Mitochondria are traditionally known as the powerhouse of the cell, but their functions
extend far beyond energy production. They are vital in cellular and organismal pathways …

Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …

The transfer of intact mitochondria between heterogeneous cell types has been confirmed in
various settings, including cancer. However, the functional implications of mitochondria …

The mitochondrial network is not only required for the production of energy, essential
cofactors and amino acids, but also serves as a signaling hub for innate immune and …

Inherited disorders of oxidative phosphorylation cause the clinically and genetically
heterogeneous diseases known as mitochondrial energy generation disorders, or …

Inflammation represents a comprehensive host response to external stimuli for the purpose
of eliminating the offending agent, minimizing injury to host tissues and fostering repair of …

Mitochondria are the key organelles involved in energy and redox homeostasis, cellular
signaling, and survival. Animal mitochondria are exquisitely sensitive to environmental …

Mitohormesis is a term used to define a biological response where the induction of a
reduced amount of mitochondrial stress leads to an increment in health and viability within a …

Temperature is a key abiotic factor affecting ecology, biogeography, and evolution of
species. Alterations of energy metabolism play an important role in adaptations and plastic …

Mitochondrially derived peptides represent a new class of circulating signalling molecules.
Humanin, the first member of this class, has been shown to have several metabolic effects …