Peptide deformylase–a promising therapeutic target for tuberculosis and antibacterial drug discovery
A Sharma, GK Khuller, S Sharma - Expert opinion on therapeutic …, 2009 - Taylor & Francis
Background: Tuberculosis (TB) remains the most important infectious disease causing
morbidity and death, due to the human pathogen Mycobacterium tuberculosis. The …
morbidity and death, due to the human pathogen Mycobacterium tuberculosis. The …
Virtual screening approach of bacterial peptide deformylase inhibitors results in new antibiotics
A Merzoug, A Chikhi, A Bensegueni… - Molecular …, 2018 - Wiley Online Library
The increasing resistance of bacteria to antibacterial therapy poses an enormous health
problem, it renders the development of new antibacterial agents with novel mechanism of …
problem, it renders the development of new antibacterial agents with novel mechanism of …
Targeting the peptide deformylase of Mycobacterium tuberculosis leads to drug discovery
V Singh, P Somvanshi - Letters in Drug Design & Discovery, 2009 - ingentaconnect.com
Peptide deformylase (PDF) is a ubiquitous bacterial metalloenzyme responsible to cleave
the formyl group from nascent polypeptides, supporting in the maturation. It plays a vital role …
the formyl group from nascent polypeptides, supporting in the maturation. It plays a vital role …
[PDF][PDF] International Review of Biophysical Chemistry (IREBIC)
C Giancola, B Vincenzo, G Valérie, G Giovanni… - 2012 - academia.edu
Molecular recognition process refers to the weak non-covalent interaction, which takes place
selectively and specifically between small ligand molecules with biological macromolecules …
selectively and specifically between small ligand molecules with biological macromolecules …