Circulating tumour DNA alterations: emerging biomarker in head and neck squamous cell carcinoma

X Huang, PHG Duijf, S Sriram, G Perera… - Journal of biomedical …, 2023 - Springer
Head and Neck cancers (HNC) are a heterogeneous group of upper aero-digestive tract
cancer and account for 931,922 new cases and 467,125 deaths worldwide. About 90% of …

Liquid biopsies in head and neck cancer: current state and future challenges

L Kong, AC Birkeland - Cancers, 2021 - mdpi.com
Simple Summary This review covers the most recent and up-to-date literature on liquid
biopsy techniques in head and neck cancer. Head and neck cancer remains a common …

Liquid BIOpsy for MiNimal RESidual DiSease Detection in Head and Neck Squamous Cell Carcinoma (LIONESS)—a personalised circulating tumour DNA analysis in …

S Flach, K Howarth, S Hackinger, C Pipinikas… - British Journal of …, 2022 - nature.com
Background Head and neck squamous cell carcinoma (HNSCC) remain a substantial
burden to global health. Cell-free circulating tumour DNA (ctDNA) is an emerging biomarker …

Application of liquid biopsy as multi-functional biomarkers in head and neck cancer

V Mishra, A Singh, X Chen, AJ Rosenberg… - British Journal of …, 2022 - nature.com
Head and neck squamous cell carcinoma (HNSCC) is a molecularly heterogeneous
disease, with a 5-year survival rate that still hovers at~ 60% despite recent advancements …

The promise of circulating tumor DNA in head and neck cancer

SS Aulakh, DA Silverman, K Young, SK Dennis… - Cancers, 2022 - mdpi.com
Simple Summary Head and neck cancer remains a challenging and deadly disease as it is
often identified in more advanced stages due to limitations in screening and surveillance …

[HTML][HTML] Liquid biopsies based on cell-free DNA as a potential biomarker in head and neck cancer

Ó Rapado-González, AM Rodríguez-Ces… - … Dental Science Review, 2023 - Elsevier
In the era of 'precision medicine', liquid biopsies based on cell-free DNA (cfDNA) have
emerged as a promising tool in the oncology field. cfDNA from cancer patients is a mixture of …

Analysis of genetic variants of frequently mutated genes in human papillomavirus‐negative primary head and neck squamous cell carcinoma, resection margins, local …

S Flach, J Kumbrink, C Walz, J Hess… - Journal of Oral …, 2022 - Wiley Online Library
Background Head and neck squamous cell carcinoma remains a substantial burden to
global health. Despite evolving therapies, 5‐year survival is< 50% and unlike in other …

[HTML][HTML] Principles of digital sequencing using unique molecular identifiers

D Andersson, FT Kebede, M Escobar… - Molecular Aspects of …, 2024 - Elsevier
Massively parallel sequencing technologies have long been used in both basic research
and clinical routine. The recent introduction of digital sequencing has made previously …

Liquid biopsy in head and neck squamous cell carcinoma: circulating tumor cells, circulating tumor DNA, and exosomes

WY Yang, LF Feng, X Meng, R Chen… - Expert Review of …, 2020 - Taylor & Francis
Introduction: Head and neck squamous cell carcinoma (HNSCC) is one of the most common
cancers worldwide. Due to a lack of reliable markers, HNSCC patients are usually …

Emerging precision diagnostics in advanced cutaneous squamous cell carcinoma

G Geidel, I Heidrich, J Kött, SW Schneider… - NPJ Precision …, 2022 - nature.com
Advanced cutaneous squamous cell carcinoma (cSCC) encompasses unresectable and
metastatic disease. Although immune checkpoint inhibition has been approved for this entity …