Sex differences in HIV infection
EP Scully - Current HIV/AIDS Reports, 2018 - Springer
Abstract Purpose of Review This review will outline the multilevel effects of biological sex on
HIV acquisition, pathogenesis, treatment response, and prospects for cure. Potential …
HIV acquisition, pathogenesis, treatment response, and prospects for cure. Potential …
Total HIV-1 DNA, a marker of viral reservoir dynamics with clinical implications
V Avettand-Fènoël, L Hocqueloux… - Clinical microbiology …, 2016 - Am Soc Microbiol
SUMMARY HIV-1 DNA persists in infected cells despite combined antiretroviral therapy
(cART), forming viral reservoirs. Recent trials of strategies targeting latent HIV reservoirs …
(cART), forming viral reservoirs. Recent trials of strategies targeting latent HIV reservoirs …
HIV DNA set point is rapidly established in acute HIV infection and dramatically reduced by early ART
J Ananworanich, N Chomont, LA Eller, E Kroon… - …, 2016 - thelancet.com
HIV DNA is a marker of HIV persistence that predicts HIV progression and remission, but its
kinetics in early acute HIV infection (AHI) is poorly understood. We longitudinally measured …
kinetics in early acute HIV infection (AHI) is poorly understood. We longitudinally measured …
HIV-1 DNA predicts disease progression and post-treatment virological control
JP Williams, J Hurst, W Stöhr, N Robinson, H Brown… - elife, 2014 - elifesciences.org
In HIV-1 infection, a population of latently infected cells facilitates viral persistence despite
antiretroviral therapy (ART). With the aim of identifying individuals in whom ART might …
antiretroviral therapy (ART). With the aim of identifying individuals in whom ART might …
The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection
An understanding of how broadly neutralizing activity develops in HIV-1-infected individuals
is needed to guide vaccine design and immunization strategies. Here we used a large panel …
is needed to guide vaccine design and immunization strategies. Here we used a large panel …
Predictors of disease progression in HIV infection: a review
SE Langford, J Ananworanich, DA Cooper - AIDS research and therapy, 2007 - Springer
During the extended clinically latent period associated with Human Immunodeficiency Virus
(HIV) infection the virus itself is far from latent. This phase of infection generally comes to an …
(HIV) infection the virus itself is far from latent. This phase of infection generally comes to an …
HIV-1 suppression and durable control by combining single broadly neutralizing antibodies and antiretroviral drugs in humanized mice
JA Horwitz, A Halper-Stromberg… - Proceedings of the …, 2013 - National Acad Sciences
Effective control of HIV-1 infection in humans is achieved using combinations of antiretroviral
therapy (ART) drugs. In humanized mice (hu-mice), control of viremia can be achieved using …
therapy (ART) drugs. In humanized mice (hu-mice), control of viremia can be achieved using …
Plasma cytokine levels during acute HIV-1 infection predict HIV disease progression
Background: Both T-cell activation during early HIV-1 infection and soluble markers of
immune activation during chronic infection are predictive of HIV disease progression …
immune activation during chronic infection are predictive of HIV disease progression …
[HTML][HTML] Focus: Infectious diseases: Mechanisms of virologic control and clinical characteristics of HIV+ elite/viremic controllers
E Gonzalo-Gil, U Ikediobi, RE Sutton - The Yale journal of biology …, 2017 - ncbi.nlm.nih.gov
Human immunodeficiency virus type 1 (HIV-1) disease is pandemic, with approximately 36
million infected individuals world-wide. For the vast majority of these individuals, untreated …
million infected individuals world-wide. For the vast majority of these individuals, untreated …
Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV-1 infection
AS Liovat, MA Rey-Cuillé, C Lécuroux, B Jacquelin… - 2012 - journals.plos.org
T cell activation levels, viral load and CD4+ T cell counts at early stages of HIV-1 infection
are predictive of the rate of progression towards AIDS. We evaluated whether the …
are predictive of the rate of progression towards AIDS. We evaluated whether the …