Role of miR-155 in inflammatory autoimmune diseases: a comprehensive review

WD Xu, SY Feng, AF Huang - Inflammation Research, 2022 - Springer
Purpose MiR-155 is a member of the microRNAs (miRNAs) family and regulates gene
expression post-transcriptionally by binding to the 3'UTR of target mRNA. MiR-155 has a …

Dynamic interplay of microRNA in diseases and therapeutic

N Kargutkar, P Hariharan, A Nadkarni - Clinical Genetics, 2023 - Wiley Online Library
MicroRNAs are the major class of small non‐coding RNAs, evolutionary conserved post‐
transcriptional regulators of gene expression. Since their discovery in 1993, they have been …

Emerging role of non-coding RNAs in regulation of T-lymphocyte function

M Taheri, DA Barth, J Kargl, O Rezaei… - Frontiers in …, 2021 - frontiersin.org
T-lymphocytes (T cells) play a major role in adaptive immunity and current immune
checkpoint inhibitor-based cancer treatments. The regulation of their function is complex …

Pancreatic cancer cell-derived microRNA-155-5p-containing extracellular vesicles promote immune evasion by triggering EHF-dependent activation of Akt/NF-κB …

S Wang, Y Gao - International Immunopharmacology, 2021 - Elsevier
Pancreatic cancer (PC)-derived EVs have been extensively investigated due to their
promising potential as disease biomarkers for diagnosis, monitoring, and treatment …

Noncoding RNAs in diagnosis and prognosis of graft‐versus‐host disease (GVHD)

MK Vajari, S Moradinasab, AM Yousefi… - Journal of Cellular …, 2022 - Wiley Online Library
Allogeneic hematopoietic stem cell transplantation (allo‐HSCT) is a functional therapy for a
plethora of hematologic malignancies and immune disorders. Graft‐versus‐host disease …

Immune modulatory microRNAs in tumors, their clinical relevance in diagnosis and therapy

C Vaxevanis, M Bachmann… - … for Immunotherapy of …, 2024 - pmc.ncbi.nlm.nih.gov
The importance of the immune system in regulating tumor growth by inducing immune cell-
mediated cytotoxicity associated with patients' outcomes has been highlighted in the past …

[HTML][HTML] Leveraging microRNAs for cellular therapy

M Hasiuk, M Dölz, R Marone, LT Jeker - Immunology Letters, 2023 - Elsevier
Abstract Owing to Karl Landsteiner's discovery of blood groups, blood transfusions became
safe cellular therapies in the early 1900s. Since then, cellular therapy made great advances …

Effects of miR‑103a‑3p on the autophagy and apoptosis of cardiomyocytes by regulating Atg5

C Zhang, J Lu, H Wang, Y Qi… - … journal of molecular …, 2019 - spandidos-publications.com
Autophagy and apoptosis are associated with cardiovascular diseases. Emerging evidence
shows that microRNAs (miRs) are critical in the development of pathological processes …

[HTML][HTML] Adipose tissue responds to stress-induced immunosuppression affecting immune response partially by miR-145-5p/S1PR1 pathway

X Wang, Y Jiang, Y Zhang, M Xia, J Li, C Man - Poultry Science, 2024 - Elsevier
Stress-induced immunosuppression (SIIS) is one of the most common problems in intensive
poultry production, which can cause immunized chickens to still develop diseases and bring …

[HTML][HTML] PRMT5 regulates T cell interferon response and is a target for acute graft-versus-host disease

KJ Snyder, NC Zitzer, Y Gao, HK Choe, NE Sell… - JCI insight, 2020 - ncbi.nlm.nih.gov
Acute graft-versus-host disease (aGVHD) is a T cell–mediated immunological disorder and
the leading cause of nonrelapse mortality in patients who receive allogeneic hematopoietic …