Abstract Background Membrane proteins (MPs) play diverse and important functions in
living organisms. They constitute 20% to 30% of the known bacterial, archaean and …

Motivation: We previously reported the development of a highly accurate statistical algorithm
for identifying β-barrel outer membrane proteins or transmembrane β-barrels (TMBBs), from …

Transmembrane beta barrel (TMB) proteins are found in the outer membranes of bacteria,
mitochondria and chloroplasts. TMBs are involved in a variety of functions such as mediating …

Several bacterial outer membrane proteins (OMPs) are known to play diverse role in
physiology including adoptive response to adverse environmental conditions and contribute …

Despite the recent advances in the determination of high-resolution membrane protein (MP)
structures, the structural and functional characterization of MPs remains extremely …

Transmembrane proteins such as transporters and channels mediate the passage of
inorganic and organic substances across biological membranes through their central pore …

Protein–protein interactions (PPI) play central roles in biological processes, motivating us to
understand the structural basis underlying affinity and specificity. In this chapter, we focus on …

Integral transmembrane (TM) proteins are essential constituents of biological membranes
where they fulfill a variety of important cellular functions. Because of difficulties with …

In this thesis, we developed, implemented and applied bioinformatics tools/techniques in
three projects that aim at characterising functional properties of membrane transport systems …

High-throughput genomic and proteomic methods provide a concise description of the
molecular constituents of a cell, whereas systems biology strives to understand the way …