Optimized minimal genome-wide human sgRNA library
Genome-wide clustered regularly interspaced short palindromic repeats (CRISPR)-based
knockout screening is revolting the genetic analysis of a cellular or molecular phenotype in …
knockout screening is revolting the genetic analysis of a cellular or molecular phenotype in …
CRISPR‐Cas9 Genome Editing and Rapid Selection of Cell Pools
D Stoyko, TO, A Hernandez, P Konstantinidou… - Current …, 2022 - Wiley Online Library
The harnessing of the CRISPR‐Cas9 system allows for quick and inexpensive genome
editing in tissue culture models. Traditional CRISPR‐Cas9 genome editing techniques rely …
editing in tissue culture models. Traditional CRISPR‐Cas9 genome editing techniques rely …
Developing next-generation methods for scoring CRISPR screening data
HN Ward - 2022 - search.proquest.com
Mapping the genotype-to-phenotype connection is a central goal of modern biology.
CRISPR screening technology powers mapping efforts by identifying relationships between …
CRISPR screening technology powers mapping efforts by identifying relationships between …
[HTML][HTML] Functional genomic analysis of adult and pediatric brain tumor isolates
Background: Adult and pediatric tumors display stark differences in their mutation spectra
and chromosome alterations. Here, we attempted to identify common and unique gene …
and chromosome alterations. Here, we attempted to identify common and unique gene …