Methionine restriction (MetR) extends lifespan across different species and exerts beneficial
effects on metabolic health and inflammatory responses. In contrast, certain cancer cells …

Adenosylhomocysteinase (AHCY) is a unique enzyme and one of the most conserved
proteins in living organisms. AHCY catalyzes the reversible break of S …

S-adenosyl-L-methionine (AdoMet)-dependent methylation is central to the regulation of
many biological processes: more than 50 AdoMet-dependent methyltransferases methylate …

Abstract Low-molecular-weight (LMW) thiols are a class of highly reactive compounds
massively involved in the maintenance of cellular redox homeostasis. They are implicated in …

Bananas (Musa spp.) are highly perishable fruit of notable economic and nutritional
relevance. Because the identification of proteins involved in metabolic pathways could help …

In Leptinotarsa decemlineata, juvenile hormones (JHs) play primary roles in the regulation
of metamorphosis, reproduction and diapause. In JH biosynthetic pathway in insect corpora …

S-adenosylhomocysteine hydrolase (SAHH), catalyzing the reversible hydrolysis of S-
adenosylhomocysteine (SAH) to adenosine and homocysteine, is a key enzyme that …

S-adenosyl-l-homocysteine hydrolase (SAHase) is a major regulator of cellular methylation
reactions that occur in eukaryotic and prokaryotic organisms. SAHase activity is also a …

Trans-methylation reactions are intrinsic to cellular metabolism in all living organisms. In
land plants, a range of substrate-specific methyltransferases catalyze the methylation of …

Developmental processes are closely connected to certain states of epigenetic information
which, among others, rely on methylation of chromatin. S-adenosylmethionine (SAM) and S …