Exploring the landscape of Babesia bovis vaccines: progress, challenges, and opportunities
Bovine babesiosis, caused by different Babesia spp. such as B. bovis, B. bigemina, B.
divergens, and B. major, is a global disease that poses a serious threat to livestock …
divergens, and B. major, is a global disease that poses a serious threat to livestock …
Immune response to Tick-Borne hemoparasites: Host adaptive immune response mechanisms as potential targets for therapies and vaccines
Tick-transmitted pathogens cause infectious diseases in both humans and animals. Different
types of adaptive immune mechanisms could be induced in hosts by these microorganisms …
types of adaptive immune mechanisms could be induced in hosts by these microorganisms …
Oral vaccination with a recombinant Lactobacillus plantarum expressing the Eimeria tenella rhoptry neck 2 protein elicits protective immunity in broiler chickens …
T Zhang, H Qu, W Zheng, Y Zhang, Y Li, T Pan, J Li… - Parasites & …, 2024 - Springer
Background Chicken coccidiosis is a protozoan disease that leads to considerable
economic losses in the poultry industry. Live oocyst vaccination is currently the most …
economic losses in the poultry industry. Live oocyst vaccination is currently the most …
Babesia bovis AMA-1, MSA-2c and RAP-1 contain conserved B and T-cell epitopes, which generate neutralizing antibodies and a long-lasting Th1 immune response …
M Hidalgo-Ruiz, S Mejia-López, RM Pérez-Serrano… - Vaccine, 2022 - Elsevier
Vaccines against bovine babesiosis must, ideally, induce a humoral immune response
characterized by neutralizing antibodies against conserved epitopes and a cellular Th1 …
characterized by neutralizing antibodies against conserved epitopes and a cellular Th1 …
Identification of novel immune correlates of protection against acute bovine babesiosis by superinfecting cattle with in vitro culture attenuated and virulent Babesia …
The apicomplexan tickborne parasites Babesia bovis and B. bigemina are the major
causative agents of bovine babesiosis, a disease that negatively affects the cattle industry …
causative agents of bovine babesiosis, a disease that negatively affects the cattle industry …
The GP-45 Protein, a Highly Variable Antigen from Babesia bigemina, Contains Conserved B-Cell Epitopes in Geographically Distant Isolates
MA Mercado-Uriostegui, LA Castro-Sánchez… - Pathogens, 2022 - mdpi.com
In B. bigemina, the 45 kilodaltons glycoprotein (GP-45) is the most studied. GP-45 is
exposed on the surface of the B. bigemina merozoite, it is believed to play a role in the …
exposed on the surface of the B. bigemina merozoite, it is believed to play a role in the …
Evaluation of the humoral and mucosal immune response of a multiepitope vaccine against COVID-19 in pigs
J Mosqueda, DJ Hernandez-Silva… - Frontiers in …, 2023 - frontiersin.org
Introduction This study evaluated the immune response to a multiepitope recombinant
chimeric protein (CHIVAX) containing B-and T-cell epitopes of the SARS-CoV-2 spike's …
chimeric protein (CHIVAX) containing B-and T-cell epitopes of the SARS-CoV-2 spike's …
Spherical Body Protein 4 from Babesia bigemina: A Novel Gene That Contains Conserved B-Cell Epitopes and Induces Cross-Reactive Neutralizing Antibodies in …
Bovine babesiosis is a tick-transmitted disease caused by intraerythrocytic protozoan
parasites of the genus Babesia. Its main causative agents in the Americas are Babesia …
parasites of the genus Babesia. Its main causative agents in the Americas are Babesia …
A conserved motif in the immune-subdominant RAP-1 related antigen of Babesia bovis contains a B-cell epitope recognized by antibodies from protected cattle
MJ Rojas, RG Bastos, J Navas, JM Laughery… - Frontiers in …, 2024 - frontiersin.org
Introduction Babesia bovis, a tick-borne apicomplexan parasite causing bovine babesiosis,
remains a significant threat worldwide, and improved and practical vaccines are needed …
remains a significant threat worldwide, and improved and practical vaccines are needed …
Developing Anti-Babesia bovis Blood Stage Vaccines: A New Perspective Regarding Synthetic Vaccines
L Cuy-Chaparro, C Reyes, EV Díaz-Guiot… - International Journal of …, 2023 - mdpi.com
Bovine babesiosis is caused by the Apicomplexa parasites from the genus Babesia. It is one
of the most important tick-borne veterinary diseases worldwide; Babesia bovis being the …
of the most important tick-borne veterinary diseases worldwide; Babesia bovis being the …